ID   H1E_CHITE               Reviewed;         237 AA.
AC   P40278;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Histone H1E;
OS   Chironomus tentans (Midge) (Camptochironomus tentans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7153;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Schulze E., Wisniewski J.R., Nagel S., Gavenis K., Grossbach U.;
RT   "The two classes of histone H1 proteins of the dipteran genus
RT   Camptochironomus are encoded by organizationally divergent genes and differ
RT   by a DNA binding motif, KAPKAP.";
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L29105; AAB53945.1; -; Genomic_DNA.
DR   AlphaFoldDB; P40278; -.
DR   SMR; P40278; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus.
FT   CHAIN           1..237
FT                   /note="Histone H1E"
FT                   /id="PRO_0000195970"
FT   DOMAIN          50..124
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          109..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..47
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..172
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..237
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   237 AA;  24689 MW;  D429364FFBCB1F3E CRC64;
     MSDPAQEVEA PVEAAPVASS PKGKKEKAPK APKAEKPKSD KPKKPKAAPT HPPVSEMVVN
     AITTLKERGG SSLIAIKKFV AAQYKVDVEK LVPFIKKFLK ASVAKGTLLQ AKGKGASGSF
     KLPPAAKKVD KPKKAPATPK PKSTKPKRVT GEKKVVKKPA AKKPEAKKAT KAAKPAAKKV
     AAKPAAKKAA APKPKAAAKP KKEVKPKKEA KPKKAAAKPA KKPAAKPAKK PAAKKAK