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H1S_SPHGR
ID   H1S_SPHGR               Reviewed;          91 AA.
AC   Q99284;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Histone H1, sperm;
DE   Flags: Fragments;
OS   Sphaerechinus granularis (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Temnopleuroida; Toxopneustidae; Sphaerechinus.
OX   NCBI_TaxID=39374;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RC   TISSUE=Sperm {ECO:0000269|PubMed:7074115};
RX   PubMed=7074115; DOI=10.1016/0167-4838(82)90015-2;
RA   Strickland W.N., Strickland M., von Holt C., Giancotti V.;
RT   "A partial structure of histone h1 from sperm of the sea urchin
RT   Sphaerechinus granulosus.";
RL   Biochim. Biophys. Acta 703:95-100(1982).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   AlphaFoldDB; Q99284; -.
DR   SMR; Q99284; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   1: Evidence at protein level;
KW   Chromosome; Direct protein sequencing; DNA-binding; Nucleus.
FT   CHAIN           1..>91
FT                   /note="Histone H1, sperm"
FT                   /id="PRO_0000273527"
FT   DOMAIN          18..91
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_CONS        25..26
FT                   /evidence="ECO:0000303|PubMed:7074115"
FT   NON_TER         91
FT                   /evidence="ECO:0000303|PubMed:7074115"
SQ   SEQUENCE   91 AA;  9729 MW;  54E1F6E542BB134B CRC64;
     PGSPQKRAAS PRKSPRKGSP KKSPMIRAAI TAMRERKGSS VAKIKSYIAA NYRVNMTNLQ
     PHIRRALRSG VASGALKQVT GTGATGRFRV G
 
 
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