H1X_CAEEL
ID H1X_CAEEL Reviewed; 232 AA.
AC Q18336; O02556;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Histone H1.X;
DE AltName: Full=Histone H1-like protein 1;
GN Name=hil-1; ORFNames=C30G7.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Bristol N2;
RX PubMed=11245572; DOI=10.1242/dev.128.7.1069;
RA Jedrusik M.A., Schulze E.;
RT "A single histone H1 isoform (H1.1) is essential for chromatin silencing
RT and germline development in Caenorhabditis elegans.";
RL Development 128:1069-1080(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00837}.
CC Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837}.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC ProRule:PRU00837}.
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DR EMBL; AF002679; AAB60893.1; -; mRNA.
DR EMBL; Z78239; CAB01632.1; -; Genomic_DNA.
DR PIR; T19583; T19583.
DR RefSeq; NP_506680.1; NM_074279.5.
DR AlphaFoldDB; Q18336; -.
DR SMR; Q18336; -.
DR STRING; 6239.C30G7.1; -.
DR EPD; Q18336; -.
DR PaxDb; Q18336; -.
DR PeptideAtlas; Q18336; -.
DR PRIDE; Q18336; -.
DR EnsemblMetazoa; C30G7.1.1; C30G7.1.1; WBGene00001852.
DR GeneID; 179993; -.
DR KEGG; cel:CELE_C30G7.1; -.
DR UCSC; C30G7.1; c. elegans.
DR CTD; 179993; -.
DR WormBase; C30G7.1; CE08476; WBGene00001852; hil-1.
DR eggNOG; KOG4012; Eukaryota.
DR HOGENOM; CLU_052897_1_1_1; -.
DR InParanoid; Q18336; -.
DR OMA; QHHPSYM; -.
DR OrthoDB; 1565299at2759; -.
DR PhylomeDB; Q18336; -.
DR PRO; PR:Q18336; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00001852; Expressed in larva and 3 other tissues.
DR GO; GO:0045111; C:intermediate filament cytoskeleton; IDA:WormBase.
DR GO; GO:0005730; C:nucleolus; IDA:WormBase.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IDA:WormBase.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0010171; P:body morphogenesis; IMP:WormBase.
DR GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR GO; GO:0040011; P:locomotion; IMP:WormBase.
DR GO; GO:0035264; P:multicellular organism growth; IMP:WormBase.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR GO; GO:0018991; P:oviposition; IMP:WormBase.
DR GO; GO:0060465; P:pharynx development; IMP:WormBase.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005819; H1/H5.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00538; Linker_histone; 1.
DR PRINTS; PR00624; HISTONEH5.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS51504; H15; 1.
PE 2: Evidence at transcript level;
KW Chromosome; DNA-binding; Nucleus; Reference proteome.
FT CHAIN 1..232
FT /note="Histone H1.X"
FT /id="PRO_0000195987"
FT DOMAIN 36..112
FT /note="H15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT REGION 142..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..195
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 25362 MW; FEA897B6FEEBBD4B CRC64;
MTTSLIHMAN HLDASTEEIS LNYVLLGHPH HERAQHHPSY MDMIKGAIQA IDNGTGSSKA
AILKYIAQNY HVGENLPKVN NHLRSVLKKA VDSGDIEQTR GHGATGSFRM GKECEKNLQV
GIPVQTKPML MLKEVRQKLE NISKAEKTKP STSSMSTNKK GKPISTMKKR GVMSKKRSSK
NKMAPKAKSH GLKKKGPATK SSGLVHKAAG AKNEAAPTTK MELRTGTRKS YC
