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H1_CHITH
ID   H1_CHITH                Reviewed;         231 AA.
AC   P21895;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Histone H1;
OS   Chironomus thummi thummi (Midge).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Chironomus.
OX   NCBI_TaxID=7155;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2172549; DOI=10.1016/s0022-2836(05)80159-7;
RA   Hankeln T., Schmidt E.R.;
RT   "New foldback transposable element TFB1 found in histone genes of the midge
RT   Chironomus thummi.";
RL   J. Mol. Biol. 215:477-482(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1769271; DOI=10.1007/bf00360683;
RA   Hankeln T., Schmidt E.R.;
RT   "The organization, localization and nucleotide sequence of the histone
RT   genes of the midge Chironomus thummi.";
RL   Chromosoma 101:25-31(1991).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; X56335; CAA39775.1; -; Genomic_DNA.
DR   PIR; S18006; S18006.
DR   AlphaFoldDB; P21895; -.
DR   SMR; P21895; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus.
FT   CHAIN           1..231
FT                   /note="Histone H1"
FT                   /id="PRO_0000195971"
FT   DOMAIN          38..112
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          124..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..170
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   231 AA;  24537 MW;  E468F648A40AF51D CRC64;
     MSDPAIEVAP VPVASPAKAK KEKKPKSDKP KKPKAPRTHP PVSDMIVNAI KTLKERGGSS
     VQAIKKFLVA QYKVDTDKLS PFIKKYLKSA VEKGQLLQTK GKGASGSFKL PAAAKKEKVV
     KKVTKKVTEK KPKKAVSKPK TGEKKVKKTI AKKPKVASAT KIKKPVAKTT KKPAAAKPTK
     KVAAKPKAAP KPKAAPKPKV AKPKKAAAPK AKKPAAEKKP KAAKKPSAKK A
 
 
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