ID   H1_ECHCR                Reviewed;         171 AA.
AC   P02257;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Histone H1, gonadal;
DE   Flags: Fragment;
OS   Echinolampas crassa (Sea urchin) (Palaeolampas crassa).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Atelostomata; Cassiduloida; Echinolampadidae; Echinolampas.
OX   NCBI_TaxID=7646;
RN   [1]
RP   PROTEIN SEQUENCE.
RA   Strickland W.N., Strickland M., von Holt C.;
RT   "A comparison of the amino acid sequences of histones H1 from the sperm of
RT   Echinolampas crassa and Parechinus angulosus.";
RL   Biochim. Biophys. Acta 700:127-129(1982).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Sperm.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A02587; HSUR1E.
DR   AlphaFoldDB; P02257; -.
DR   SMR; P02257; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   1: Evidence at protein level;
KW   Chromosome; Direct protein sequencing; DNA-binding; Nucleus.
FT   CHAIN           1..>171
FT                   /note="Histone H1, gonadal"
FT                   /id="PRO_0000195938"
FT   DOMAIN          37..111
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          133..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..35
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         171
SQ   SEQUENCE   171 AA;  18310 MW;  34DE1B20013E06BB CRC64;
     AASPQKRAAS PRKSPKKSPR KSPKKKSPRK RKARSAAHPP VIDMITAAIA AQKERRGSSV
     AKIQSYIAAK YRCDINALNP HIRRALKNQV KSGALKQVSG VGATGRFRVG AVKRSAASAN
     KLKATREKAR ARAKAKKAKA AARRKAAAAK RKAAAAKRRA AKKARKAKAK P