H1_EUPEU
ID H1_EUPEU Reviewed; 135 AA.
AC P32103;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Histone H1, macronuclear;
OS Euplotes eurystomus (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Hypotrichia; Euplotida; Euplotidae; Euplotes.
OX NCBI_TaxID=5941;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX PubMed=8346042; DOI=10.1093/nar/21.15.3586;
RA Hauser L.J., Treat M.L., Olins D.E.;
RT "Cloning and analysis of the macronuclear gene for histone H1 from Euplotes
RT eurystomus.";
RL Nucleic Acids Res. 21:3586-3586(1993).
CC -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC chains into higher-order structures.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome. Note=Macronuclei.
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DR EMBL; L15293; AAA29125.1; -; Genomic_DNA.
DR PIR; S34952; S34952.
DR AlphaFoldDB; P32103; -.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Chromosome; Direct protein sequencing; DNA-binding; Nucleus.
FT INIT_MET 1
FT /note="Removed"
FT CHAIN 2..135
FT /note="Histone H1, macronuclear"
FT /id="PRO_0000195978"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..51
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..135
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 135 AA; 13556 MW; D9E8BB529319EE6B CRC64;
MPAKTATAVK RTTTTKKSAA KRKTSKAVKK AGKRTQSKAK GAQKVKKAAT RRTPSKSAGA
RKATKKAGAR KASTKRSATK KTTAAPAAAA APATDAPAAA ATPSKATGSA KKASARKSSA
KKPAKGGKKK SAKKN