ID   H1_LYTPI                Reviewed;         210 AA.
AC   P06144;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Late histone H1;
OS   Lytechinus pictus (Painted sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Temnopleuroida; Toxopneustidae; Lytechinus.
OX   NCBI_TaxID=7653;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Embryo;
RX   PubMed=3022245; DOI=10.1093/nar/14.20.8121;
RA   Knowles J.A., Childs G.J.;
RT   "Comparison of the late H1 histone genes of the sea urchins Lytechinus
RT   pictus and Strongelocentrotus purpuratus.";
RL   Nucleic Acids Res. 14:8121-8133(1986).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; X04488; CAA28177.1; -; Genomic_DNA.
DR   PIR; A25550; A25550.
DR   AlphaFoldDB; P06144; -.
DR   SMR; P06144; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus.
FT   CHAIN           1..210
FT                   /note="Late histone H1"
FT                   /id="PRO_0000195939"
FT   DOMAIN          17..91
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..119
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        120..210
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   210 AA;  21746 MW;  08C38F64894007E2 CRC64;
     MSAAKPKTAK KARAAPAHPP TSQMVVAAIT ALKERGGSSN QAIKKYIAAN YKVDINKQAT
     FIKRALKAGV ANGTLVQVKG KGASGSFKLG KVKAGKTEAQ KARAAAKKAK LAAKKKEQKE
     KKAAKTKARK EKLAAKKAAK KAAKKVKKPA AKAKKPAKKA AKKPAAKKAA KKPAAKKPAK
     KAAKKPAAKK AAKPAKKAAK KPAAKKAAKK