H4_SOYBN
ID H4_SOYBN Reviewed; 103 AA.
AC P0CG89; C6TDS7;
DT 10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT 10-AUG-2010, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Histone H4;
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Cheung F., Xiao Y., Chan A., Moskal W., Town C.D.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the histone H4 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ACU19979.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA. A chimeric cDNA originating from chromosomes 19 and 20.; Evidence={ECO:0000305};
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DR EMBL; BT095742; ACU19979.1; ALT_SEQ; mRNA.
DR RefSeq; NP_001237495.1; NM_001250566.2.
DR RefSeq; XP_003521335.1; XM_003521287.3.
DR RefSeq; XP_003535987.1; XM_003535939.3.
DR RefSeq; XP_003538030.1; XM_003537982.3.
DR RefSeq; XP_003538258.1; XM_003538210.3.
DR RefSeq; XP_003538259.1; XM_003538211.3.
DR RefSeq; XP_003538260.1; XM_003538212.3.
DR RefSeq; XP_003539748.1; XM_003539700.3.
DR RefSeq; XP_003542580.3; XM_003542532.3.
DR RefSeq; XP_003544868.1; XM_003544820.3.
DR RefSeq; XP_003549448.1; XM_003549400.3.
DR RefSeq; XP_003551292.3; XM_003551244.3.
DR RefSeq; XP_003555742.1; XM_003555694.3.
DR RefSeq; XP_006597302.1; XM_006597239.2.
DR RefSeq; XP_014624656.1; XM_014769170.1.
DR AlphaFoldDB; P0CG89; -.
DR BMRB; P0CG89; -.
DR SMR; P0CG89; -.
DR STRING; 3847.GLYMA03G32881.1; -.
DR PRIDE; P0CG89; -.
DR EnsemblPlants; KRG88688; KRG88688; GLYMA_U033600.
DR EnsemblPlants; KRG90333; KRG90333; GLYMA_20G083800.
DR EnsemblPlants; KRG98308; KRG98308; GLYMA_18G064300.
DR EnsemblPlants; KRH02870; KRH02870; GLYMA_17G063200.
DR EnsemblPlants; KRH10344; KRH10344; GLYMA_15G043200.
DR EnsemblPlants; KRH10345; KRH10345; GLYMA_15G043200.
DR EnsemblPlants; KRH16996; KRH16996; GLYMA_14G190800.
DR EnsemblPlants; KRH19969; KRH19969; GLYMA_13G147000.
DR EnsemblPlants; KRH24981; KRH24981; GLYMA_12G074500.
DR EnsemblPlants; KRH30344; KRH30344; GLYMA_11G177800.
DR EnsemblPlants; KRH30345; KRH30345; GLYMA_11G177900.
DR EnsemblPlants; KRH30347; KRH30347; GLYMA_11G178100.
DR EnsemblPlants; KRH30348; KRH30348; GLYMA_11G178200.
DR EnsemblPlants; KRH33582; KRH33582; GLYMA_10G133500.
DR EnsemblPlants; KRH67535; KRH67535; GLYMA_03G171400.
DR EnsemblPlants; KRH72633; KRH72633; GLYMA_02G224100.
DR GeneID; 100305586; -.
DR GeneID; 100777359; -.
DR GeneID; 100778317; -.
DR GeneID; 100779597; -.
DR GeneID; 100784085; -.
DR GeneID; 100784197; -.
DR GeneID; 100788767; -.
DR GeneID; 100793106; -.
DR GeneID; 100799680; -.
DR GeneID; 100800769; -.
DR GeneID; 100805597; -.
DR GeneID; 100818211; -.
DR GeneID; 100818748; -.
DR GeneID; 100819286; -.
DR GeneID; 100819422; -.
DR Gramene; KRG88688; KRG88688; GLYMA_U033600.
DR Gramene; KRG90333; KRG90333; GLYMA_20G083800.
DR Gramene; KRG98308; KRG98308; GLYMA_18G064300.
DR Gramene; KRH02870; KRH02870; GLYMA_17G063200.
DR Gramene; KRH10344; KRH10344; GLYMA_15G043200.
DR Gramene; KRH10345; KRH10345; GLYMA_15G043200.
DR Gramene; KRH16996; KRH16996; GLYMA_14G190800.
DR Gramene; KRH19969; KRH19969; GLYMA_13G147000.
DR Gramene; KRH24981; KRH24981; GLYMA_12G074500.
DR Gramene; KRH30344; KRH30344; GLYMA_11G177800.
DR Gramene; KRH30345; KRH30345; GLYMA_11G177900.
DR Gramene; KRH30347; KRH30347; GLYMA_11G178100.
DR Gramene; KRH30348; KRH30348; GLYMA_11G178200.
DR Gramene; KRH33582; KRH33582; GLYMA_10G133500.
DR Gramene; KRH67535; KRH67535; GLYMA_03G171400.
DR Gramene; KRH72633; KRH72633; GLYMA_02G224100.
DR KEGG; gmx:100305586; -.
DR KEGG; gmx:100777359; -.
DR KEGG; gmx:100778317; -.
DR KEGG; gmx:100779597; -.
DR KEGG; gmx:100784085; -.
DR KEGG; gmx:100784197; -.
DR KEGG; gmx:100788767; -.
DR KEGG; gmx:100793106; -.
DR KEGG; gmx:100799680; -.
DR KEGG; gmx:100800769; -.
DR KEGG; gmx:100805597; -.
DR KEGG; gmx:100818211; -.
DR KEGG; gmx:100818748; -.
DR KEGG; gmx:100819286; -.
DR KEGG; gmx:100819422; -.
DR eggNOG; KOG3467; Eukaryota.
DR HOGENOM; CLU_109117_2_3_1; -.
DR InParanoid; P0CG89; -.
DR OMA; QKEHING; -.
DR OrthoDB; 1594208at2759; -.
DR Proteomes; UP000008827; Chromosome 10.
DR Proteomes; UP000008827; Chromosome 11.
DR Proteomes; UP000008827; Chromosome 12.
DR Proteomes; UP000008827; Chromosome 13.
DR Proteomes; UP000008827; Chromosome 14.
DR Proteomes; UP000008827; Chromosome 15.
DR Proteomes; UP000008827; Chromosome 17.
DR Proteomes; UP000008827; Chromosome 18.
DR Proteomes; UP000008827; Chromosome 2.
DR Proteomes; UP000008827; Chromosome 20.
DR Proteomes; UP000008827; Chromosome 3.
DR Genevisible; P0CG89; GM.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR CDD; cd00076; H4; 1.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR035425; CENP-T/H4_C.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR001951; Histone_H4.
DR InterPro; IPR019809; Histone_H4_CS.
DR Pfam; PF15511; CENP-T_C; 1.
DR PRINTS; PR00623; HISTONEH4.
DR SMART; SM00417; H4; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
DR PROSITE; PS00047; HISTONE_H4; 1.
PE 3: Inferred from homology;
KW Acetylation; Chromosome; DNA-binding; Methylation; Nucleosome core;
KW Nucleus; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..103
FT /note="Histone H4"
FT /id="PRO_0000395967"
FT DNA_BIND 17..21
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000250"
FT MOD_RES 6
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
FT MOD_RES 9
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
FT MOD_RES 13
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
FT MOD_RES 17
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
FT MOD_RES 21
FT /note="N6-acetyllysine; alternate"
FT /evidence="ECO:0000250"
FT MOD_RES 21
FT /note="N6-methyllysine; alternate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 103 AA; 11409 MW; A9FD57725A2A7598 CRC64;
MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK
IFLENVIRDA VTYTEHARRK TVTAMDVVYA LKRQGRTLYG FGG
