ID   H5_ANSAN                Reviewed;         193 AA.
AC   P02258;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Histone H5;
OS   Anser anser anser (Western greylag goose).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anserinae; Anser.
OX   NCBI_TaxID=8844;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=518607; DOI=10.1016/0006-291x(79)91191-4;
RA   Yaguchi M., Roy C., Seligy V.L.;
RT   "Complete amino acid sequence of goose erythrocyte H5 histone and the
RT   homology between H1 and H5 histones.";
RL   Biochem. Biophys. Res. Commun. 90:1400-1406(1979).
CC   -!- FUNCTION: Histone H5 performs the same function as H1, being necessary
CC       for the condensation of nucleosome chains into higher order structures,
CC       and replaces histone H1 in certain cells.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Erythroid cells.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   PIR; A02588; HSGS5.
DR   AlphaFoldDB; P02258; -.
DR   SMR; P02258; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   1: Evidence at protein level;
KW   Chromosome; Direct protein sequencing; DNA condensation; DNA-binding;
KW   Nucleus.
FT   CHAIN           1..193
FT                   /note="Histone H5"
FT                   /id="PRO_0000196003"
FT   DOMAIN          25..98
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          80..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..193
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   193 AA;  20900 MW;  44C6916BE61A04A3 CRC64;
     TDSPIPAPAP AAKPKRARAP RKPASHPTYS EMIAAAIRAD KSRGGSSRQS IQKYVKSHYK
     VGQHADLQIK LAIRRLLTTG VLKQTKGVGA SGSFRLAKGD KAKRSPAGRK KKKKAARKST
     SPKKAARPRK ARSPAKKPKA AARKARKKSR ASPKKAKKPK TVKAKSLKTS KPKKARRSKP
     RAKSGARKSP KKK