ID   H5_CAIMO                Reviewed;         194 AA.
AC   P06513;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Histone H5;
OS   Cairina moschata (Muscovy duck).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae;
OC   Anatinae; Cairina.
OX   NCBI_TaxID=8855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6492153; DOI=10.1016/0022-2836(84)90135-9;
RA   Doenecke D., Toenjes R.;
RT   "Conserved dyad symmetry structures at the 3' end of H5 histone genes.
RT   Analysis of the duck H5 gene.";
RL   J. Mol. Biol. 178:121-135(1984).
CC   -!- FUNCTION: Histone H5 performs the same function as H1, being necessary
CC       for the condensation of nucleosome chains into higher order structures,
CC       and replaces histone H1 in certain cells.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Erythroid cells.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; X01065; CAA25530.1; -; Genomic_DNA.
DR   PIR; S07260; S07260.
DR   AlphaFoldDB; P06513; -.
DR   SMR; P06513; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; DNA condensation; DNA-binding; Nucleus.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..194
FT                   /note="Histone H5"
FT                   /id="PRO_0000196004"
FT   DOMAIN          26..99
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..194
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   194 AA;  21005 MW;  E95A3971BCAC2910 CRC64;
     MTDSPIPAPA PAAKPKRAKA PRKPASHPSY SEMIVAAIRA EKSRGGSSRQ SIQKYVKSHY
     KVGQHADLQI KLSIRRLLAA GVLKQTKGVG ASGSYRLAKG DKAKKSPAGR KKKKKAARRS
     TSPRKAARPR KARSPAKKPK AAARKARKKS RASPKKAKKP KTVKAKSLKT SKVKKAKRSK
     PRAKSGARKS PKKK