ID   H962R_ASFB7             Reviewed;         962 AA.
AC   Q65162;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Putative primase C962R;
DE            EC=3.6.4.-;
GN   OrderedLocusNames=Ba71V-071; ORFNames=C962R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus helicase C962R family.
CC       {ECO:0000305}.
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DR   EMBL; U18466; AAA65301.1; -; Genomic_DNA.
DR   RefSeq; NP_042765.1; NC_001659.2.
DR   GeneID; 22220301; -.
DR   KEGG; vg:22220301; -.
DR   Proteomes; UP000000624; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   InterPro; IPR014819; PriCT_2.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF08707; PriCT_2; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; DNA replication; Helicase; Hydrolase; Late protein;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..962
FT                   /note="Putative primase C962R"
FT                   /id="PRO_0000373375"
FT   DOMAIN          607..775
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
FT   BINDING         636..643
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
SQ   SEQUENCE   962 AA;  111252 MW;  11E062A4F2935EBA CRC64;
     MREESWEDHD TIQLTAQRKY LAEVQALETL LTRELSAFLT EPGSKKTNII NRITGKTYAL
     PSTELLRLYE HLEQCRKQGA LMYFLERQGT YSGLMLDYDL KLNTNAVPPL EPPALSRLCH
     RIFVHIKNSS VLPEGSHKIH FFFTLKPEVV QGKYGFHVLI PGLKLAASTK KSIIGSLQHD
     ATVQKILHEQ GVANPESCLD PHSASVPSLL YGSSKLNHKP YQLKTGFELV FDSSDPDYIP
     IHQIKNIESY NLVSELSLTN EQGSLVRPVY CAADIAAEKE EEIPTDDHSL SILMLHDPEA
     RYLHKILNLL PPEYYVEYPL WSNVVFALAN TSANYRPLAE WFSQKCPEKW NTGGKEKLEK
     LWNDASRHTE KKITKRSIMY WAHKHAPQQY KEIVEQGYFS ILAEYVYSYN GMLEHYMIAK
     VIYAMMGNKF VVDVDSNGKY VWFEFVLPGQ PMNQGEIWKW RKEVNPDELH IYISENFSRV
     MDRITEHIKY HLSQPHETNI LNYYKKLLKA FERSKSKIFN DSFKKGVIRQ AEFLFRQRSF
     IQTLDTNPHL LGVGNGVLSI ETIPAKLINH FHEHPIHQYT HICYVPFNPE NPWTKLLLNA
     LQDIIPELDA RLWIMFYLST AIFRGLKEAL MLLWLGGGCN GKTFLMRLVA MVLGDHYASK
     LNISLLTSCR ETAEKPNSAF MRLKGRGYGY FEETNKSEVL NTSRLKEMVN PGDVTARELN
     QKQESFQMTA TMVAASNYNF IIDTTDHGTW RRLRHYRSKV KFCHNPDPGN PYEKKEDPRF
     IHEYIMDPDC QNAFFSILVY FWEKLQKEYN GQIKKVFCPT IESETEAYRK SQDTLHRFIT
     ERVVESPSAE TVYNLSEVVT AYAEWYNANI NVKRHIALEL SQELENSVLE KYLQWSPNKT
     RILKGCRILH KFETLQPGES YIGVSTAGTL LNTPICEPKN KWWEWSPNLS APPEKEASAP
     TP