ID   H962R_ASFM2             Reviewed;         962 AA.
AC   Q8V9U4;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Putative primase C962R {ECO:0000305};
DE            EC=3.6.4.-;
GN   OrderedLocusNames=Mal-079; ORFNames=L09AR;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 615-962.
RA   Roberts P.C., Lu Z., Rock D.L.;
RT   "Nucleotide sequence and analysis of 16.25 kilobase pairs of the African
RT   swine fever virus genome that span the central variable region.";
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus helicase C962R family.
CC       {ECO:0000305}.
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DR   EMBL; L00966; AAL31318.1; -; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   InterPro; IPR014819; PriCT_2.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF08707; PriCT_2; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Helicase; Hydrolase; Late protein;
KW   Nucleotide-binding.
FT   CHAIN           1..962
FT                   /note="Putative primase C962R"
FT                   /id="PRO_0000373379"
FT   DOMAIN          607..775
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
FT   BINDING         636..643
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
SQ   SEQUENCE   962 AA;  111418 MW;  C6212B57D0EA738B CRC64;
     MREESWEEHD TIQLTAQRKY LAEVQALETL LTRELSVFLT EPGSKKTNII NRITGKTYAL
     PSTELLRLYE HLEQCRKQGA LMYFLERQGT YSGLMLDYDL KLNTNAAPPL ESPALSRLCH
     RIFMHIKNTS VLPEGSHKIH FFFTLKPEVV QGKYGFHVLI PGLKLAASTK KSIIASLQHD
     ATVQKILHEQ GVTNPESCLD PHSASVPSLL YGSSKLNHKP YQLKTGFELV FDSSDPDYIP
     IHQIKNIEAY NLVSELSLTN EQGSLVKPVY CEADIAAEKE EEIPVDDHSL SILMLHDPEA
     RYLHKILNLL PPEYYVEYPL WSNVVFALAN TSANYRPLAE WFSQKCPEKW NTGGKEKLEK
     LWNDASRHTE KKITKRSIMY WAHKHAPQQY KEIVEQGYFS ILAEYVYSYN GTLEHYMIAK
     VIYAMMGNKF VVDVDSNGKY VWFEFVLPGQ PMNQGEIWKW RKEVNPDELH IYISENFSRV
     MDRITEHIKY HLSQPHETNI LNYYKKLLKA FERSKSKIFN DSFKKGVIRQ AEFLFRQRSF
     IQTLDTNPHL LGVGNGVLSI ETIPAKLINH FHEHPIHQYT HICYEPFNPE NPWTKLLLNA
     LQDIIPELDA RLWIMFYLST AIFRGLKEAL MLLWLGGGCN GKTFLMRLVA MVLGDHYASK
     LNISLLTSCR ETAEKPNSAF MRLKGRGYGY FEETNKSEVL NTSRLKEMVN PGDVTARELN
     QKQESFQMTA TMVAASNYNF IIDTTDHGTW RRLRHYRSKV KFCHNPDPNN SYEKKEDPRF
     IHEYIMDPNC QNAFFSILVY FWEKLQKEYN GQIKKVFCPT IESETEAYRK SQDTLHRFIT
     ERVVESPSAE TVYNLSEVVT AYAEWYNTNI NVKRHIALEL SQELENSVLE KYLQWSPNKT
     RILKGCRILH KFETLQPGES YIGVSTAGTL LNTPICEPKN KWWEWSPNPS APPEKEASAP
     TP