HAK12_ORYSJ
ID HAK12_ORYSJ Reviewed; 793 AA.
AC Q8VXB1; A3BQM5; B7EGA9; Q0J7B3;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Putative potassium transporter 12;
DE AltName: Full=OsHAK12;
GN Name=HAK12; OrderedLocusNames=Os08g0206400, LOC_Os08g10550;
GN ORFNames=OsJ_26409;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=12376644; DOI=10.1104/pp.007781;
RA Banuelos M.A., Garciadeblas B., Cubero B., Rodriguez-Navarro A.;
RT "Inventory and functional characterization of the HAK potassium
RT transporters of rice.";
RL Plant Physiol. 130:784-795(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY.
RX PubMed=19302972; DOI=10.1016/s1673-8527(08)60103-4;
RA Yang Z., Gao Q., Sun C., Li W., Gu S., Xu C.;
RT "Molecular evolution and functional divergence of HAK potassium transporter
RT gene family in rice (Oryza sativa L.).";
RL J. Genet. Genomics 36:161-172(2009).
CC -!- FUNCTION: High-affinity potassium transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8VXB1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8VXB1-2; Sequence=VSP_037673;
CC -!- SIMILARITY: Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF23152.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ427981; CAD21002.1; -; Genomic_DNA.
DR EMBL; AP003875; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AP008214; BAF23152.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000145; EAZ41864.1; -; Genomic_DNA.
DR EMBL; AK069377; BAG91406.1; -; mRNA.
DR RefSeq; XP_015650350.1; XM_015794864.1. [Q8VXB1-1]
DR AlphaFoldDB; Q8VXB1; -.
DR STRING; 39947.Q8VXB1; -.
DR PaxDb; Q8VXB1; -.
DR PRIDE; Q8VXB1; -.
DR GeneID; 9270408; -.
DR KEGG; osa:9270408; -.
DR InParanoid; Q8VXB1; -.
DR OrthoDB; 332035at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006813; P:potassium ion transport; IBA:GO_Central.
DR InterPro; IPR003855; K+_transporter.
DR PANTHER; PTHR30540; PTHR30540; 1.
DR Pfam; PF02705; K_trans; 1.
DR TIGRFAMs; TIGR00794; kup; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..793
FT /note="Putative potassium transporter 12"
FT /id="PRO_0000209099"
FT TOPO_DOM 1..54
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..87
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 109..175
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 176..196
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 197..215
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 216..236
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 237..238
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 239..259
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 260..289
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 290..310
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 311..315
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 316..338
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 339..359
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 360..380
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 381..411
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 412..432
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 433..444
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 445..465
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 466..468
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 469..489
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 490..496
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 497..517
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 518..793
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 266
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 434
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 1..211
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_037673"
SQ SEQUENCE 793 AA; 88686 MW; A8D272C4B41CB8B1 CRC64;
MASISDSETT NHGSIWDLDQ NLDQPMDEEA SRLKNMYTEK KFSSILLLRL AFQSLGVVFG
DLGTSPLYVF YNIFPHGVDD DEDVIGALSL IIYTLTLIPL MKYVFVVLRA NDNGQGGTFA
LYSLLCRHAK VSTIPNQHKT DEELTTYSRQ TYEENSLAAK IKRWLEGHVY KKNCLLILVL
IGTCTAIGDG ILTPAISVLS ASGGIRVQNQ KMSTDVVVVV AVIILIGLFS MQHYGTDKVG
WLFAPIVLLW FILIGTIGAL NIHKYNSSVL KAYNPVYIYR YFRRGKSESW TSLGGIMLSI
TGTEALYADL CHFPVLAIQI AFTLVVFPCL LLAYTGQAAY IISNKDHVVD AFYRSIPDTI
YWPVFIIATL AAIVASQATI SATYSIIKQA LALGCFPRVS VVHTSKKFLG QIYIPDINWV
LMILCIAVTA GFKNQSQIGN AYGTAVVIVM LVTTFLMVPI MLLVWKSHWI LVVIFIVLSL
MVELPYFTAC INKVDQGGWV PLVVATTCFI IMYVWHFCTV KRYEFEMHSK VSMAWILGLG
PSLGLVRVPG IGFVYTELAS GVPHIFSHFI TNLPAIHSVV VFVCVKYLPV YTVPTEERFI
VKRIGPKNFH MFRCVARYGY KDIHKRDDDF EKMLLDRLLL FVRLESMMDD YSDSEDFTMM
EEKTQGSSNA LLLTGKAGSN TMCSTGDLSY SSQDSIVPAK SPIRGNSLTR YSSQTFGDEL
EFLNLEFLNR CKDAGVVHIL GNTVVHARPD SGIIKKVAVN YVFAFLRKIC RENSVIFNVP
HESLLNVGQI YYI
