ID   HAUS2_PONAB             Reviewed;         204 AA.
AC   Q5RE16;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=HAUS augmin-like complex subunit 2;
DE   AltName: Full=Centrosomal protein of 27 kDa;
DE            Short=Cep27;
GN   Name=HAUS2; Synonyms=CEP27;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the HAUS augmin-like complex. The complex
CC       interacts with the gamma-tubulin ring complex and this interaction is
CC       required for spindle assembly (By similarity). Interacts with EML3
CC       (phosphorylated form) (By similarity). {ECO:0000250|UniProtKB:Q9NVX0}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250|UniProtKB:Q9NVX0}. Cytoplasm,
CC       cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9NVX0}. Note=Localizes to
CC       interphase centrosomes and to mitotic spindle microtubules.
CC       {ECO:0000250|UniProtKB:Q9NVX0}.
CC   -!- SIMILARITY: Belongs to the HAUS2 family. {ECO:0000305}.
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DR   EMBL; CR857723; CAH89991.1; -; mRNA.
DR   RefSeq; NP_001124943.1; NM_001131471.1.
DR   AlphaFoldDB; Q5RE16; -.
DR   SMR; Q5RE16; -.
DR   PRIDE; Q5RE16; -.
DR   Ensembl; ENSPPYT00000007550; ENSPPYP00000007250; ENSPPYG00000006398.
DR   GeneID; 100171815; -.
DR   KEGG; pon:100171815; -.
DR   CTD; 55142; -.
DR   GeneTree; ENSGT00390000004927; -.
DR   HOGENOM; CLU_096512_1_0_1; -.
DR   InParanoid; Q5RE16; -.
DR   Proteomes; UP000001595; Chromosome 15.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0070652; C:HAUS complex; ISS:UniProtKB.
DR   GO; GO:1990498; C:mitotic spindle microtubule; ISS:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007098; P:centrosome cycle; ISS:UniProtKB.
DR   GO; GO:0051225; P:spindle assembly; ISS:UniProtKB.
DR   InterPro; IPR028346; HAUS2.
DR   InterPro; IPR026242; HAUS2_metazoa.
DR   PANTHER; PTHR16039; PTHR16039; 1.
DR   Pfam; PF15003; HAUS2; 1.
DR   PRINTS; PR02088; HAUSAUGMINL2.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Microtubule; Mitosis; Reference proteome.
FT   CHAIN           1..204
FT                   /note="HAUS augmin-like complex subunit 2"
FT                   /id="PRO_0000089486"
FT   COILED          54..84
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   204 AA;  23272 MW;  3924B4985516FE61 CRC64;
     MAAANPWDPA SAPNGAGLVL GHFIASGMVN QKNLEIELLK LEKDTADVVH PFFLAQKCHT
     LQSMNNHLEA VLKEKRSLRQ RLLKPMCQEN LPIEAVYHRY MVHLLELAVT FIERLETHLE
     TIRNIPHLAA NLKKMNQALA KMDILVTETE ELAENILKWR KQQNEVSSCI PKILAEESYL
     YKHDIIMPPL PFTSKVHVQT INAK