ID   HBA1_SAAHA              Reviewed;          90 AA.
AC   P18979;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Hemoglobin subunit alpha-1;
DE   AltName: Full=Alpha-1-globin;
DE   AltName: Full=Hemoglobin alpha-1 chain;
DE   Flags: Fragment;
OS   Saara hardwickii (Indian spiny-tailed lizard) (Uromastyx hardwickii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Acrodonta; Agamidae; Uromastycinae; Saara.
OX   NCBI_TaxID=40250;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=6628672; DOI=10.1016/0014-5793(83)80774-1;
RA   Naqvi S., Zaidi Z.H., von Bahr-Lindstroem H., Carlquist M., Joernvall H.;
RT   "Characterization of hemoglobin from the lizard Uromastix hardwickii.";
RL   FEBS Lett. 162:290-295(1983).
CC   -!- FUNCTION: Involved in oxygen transport from the lung to the various
CC       peripheral tissues.
CC   -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains.
CC   -!- TISSUE SPECIFICITY: Red blood cells.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; A05300; A05300.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR002338; Hemoglobin_a-typ.
DR   InterPro; IPR002339; Hemoglobin_pi.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00612; ALPHAHAEM.
DR   PRINTS; PR00815; PIHAEM.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport;
KW   Transport.
FT   CHAIN           1..>90
FT                   /note="Hemoglobin subunit alpha-1"
FT                   /id="PRO_0000052796"
FT   NON_TER         90
SQ   SEQUENCE   90 AA;  9989 MW;  648E3982683AA962 CRC64;
     VLTDDDKNHV RAIWGHVSNN PEAFGAEALY RLFTAHPASK TYFSHFDLHE NSAQIRXXXX
     KVVDALTQAV NNLDDLSGAI SKLSDLHAEK