ID   HBAP1_DANRE             Reviewed;         449 AA.
AC   Q6AXL5; B0S6T4;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 2.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=HSPB1-associated protein 1 homolog;
GN   Name=hspbap1; ORFNames=si:dkey-25l23.5, zgc:100975;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in cellular stress response. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; BX548071; CAQ14575.1; -; Genomic_DNA.
DR   EMBL; BC079489; AAH79489.1; -; mRNA.
DR   RefSeq; NP_001003777.1; NM_001003777.2.
DR   AlphaFoldDB; Q6AXL5; -.
DR   SMR; Q6AXL5; -.
DR   STRING; 7955.ENSDARP00000039912; -.
DR   PaxDb; Q6AXL5; -.
DR   PRIDE; Q6AXL5; -.
DR   Ensembl; ENSDART00000039913; ENSDARP00000039912; ENSDARG00000033771.
DR   GeneID; 445320; -.
DR   KEGG; dre:445320; -.
DR   CTD; 79663; -.
DR   ZFIN; ZDB-GENE-040808-38; hspbap1.
DR   eggNOG; KOG2132; Eukaryota.
DR   GeneTree; ENSGT00940000159893; -.
DR   HOGENOM; CLU_016785_5_1_1; -.
DR   InParanoid; Q6AXL5; -.
DR   OMA; QRMMSKS; -.
DR   OrthoDB; 1385616at2759; -.
DR   PhylomeDB; Q6AXL5; -.
DR   TreeFam; TF315056; -.
DR   PRO; PR:Q6AXL5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 9.
DR   Bgee; ENSDARG00000033771; Expressed in ovary and 21 other tissues.
DR   ExpressionAtlas; Q6AXL5; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IBA:GO_Central.
DR   InterPro; IPR041667; Cupin_8.
DR   InterPro; IPR003347; JmjC_dom.
DR   Pfam; PF13621; Cupin_8; 1.
DR   SMART; SM00558; JmjC; 1.
DR   PROSITE; PS51184; JMJC; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..449
FT                   /note="HSPB1-associated protein 1 homolog"
FT                   /id="PRO_0000284116"
FT   DOMAIN          102..266
FT                   /note="JmjC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00538"
FT   REGION          385..416
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..416
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        47
FT                   /note="K -> E (in Ref. 2; AAH79489)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        92..94
FT                   /note="PFL -> AFS (in Ref. 2; AAH79489)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        309
FT                   /note="V -> A (in Ref. 2; AAH79489)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        325
FT                   /note="E -> Q (in Ref. 2; AAH79489)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        408..409
FT                   /note="EN -> GS (in Ref. 2; AAH79489)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   449 AA;  50992 MW;  D766238840994B3C CRC64;
     MSSKPFTPEE ARRIVQVLQK PAVFLNMTTD WPALHWTVEH LSACLTKRIR FRVGKRSEDM
     APLFETECSY VEATIKEFLS WTANDGEPLV GPFLDYHCKE FWAYADYKYI AQLFQDKPAM
     FQDVVWSDFG FPGRDGRDST LWIGTQCANT PCHLDSYGCN LVFQIQGRKR WHLFPPDDTA
     CLYPTRVPYE ESSVFSHVNV IRPDLKKFPA YGRARLYTVT LQPGQVLFVP RHWWHYVESV
     DPVTVSVNSW IEMDMDDEAR VAEALTKTIV CAVKSSPSLD NSDQWLNPTE DGVSSHDENM
     QYLNLAVKVC MNKKRDDIED QPKAEAVKRD FSGVLKSPAS PPSLVSFGPH LIPVHLTEKP
     QCSSTKDSCC FSCTDSPQCQ ITTKDQDKLR SDNKLGQRSG QSVLQDTENP GGSGEMHIST
     NDVLECLVHP DVIALVTRLI MCRQRELHS