ID   HBAZ_NOTEU              Reviewed;          79 AA.
AC   P81044;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Hemoglobin subunit zeta;
DE   AltName: Full=Hemoglobin zeta chain;
DE   AltName: Full=Zeta-globin;
DE   Flags: Fragments;
OS   Notamacropus eugenii (Tammar wallaby) (Macropus eugenii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Diprotodontia; Macropodidae; Notamacropus.
OX   NCBI_TaxID=9315;
RN   [1]
RP   PROTEIN SEQUENCE, ACETYLATION AT SER-1, SUBUNIT, IDENTIFICATION BY MASS
RP   SPECTROMETRY, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Blood;
RX   PubMed=9342240; DOI=10.1111/j.1432-1033.1997.00864.x;
RA   Holland R.A.B., Gooley A.A.;
RT   "Characterization of the embryonic globin chains of the marsupial Tammar
RT   wallaby, Macropus eugenii.";
RL   Eur. J. Biochem. 248:864-871(1997).
CC   -!- FUNCTION: The zeta chain is an alpha-type chain of mammalian embryonic
CC       hemoglobin.
CC   -!- SUBUNIT: Heterotetramer of two zeta chains and two epsilon chains.
CC       {ECO:0000269|PubMed:9342240}.
CC   -!- DEVELOPMENTAL STAGE: Detected in blood from prenatal and neonatal
CC       animals. {ECO:0000269|PubMed:9342240}.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   iPTMnet; P81044; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 2.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   Pfam; PF00042; Globin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Heme; Iron; Metal-binding;
KW   Oxygen transport; Phosphoprotein; Transport.
FT   CHAIN           1..>79
FT                   /note="Hemoglobin subunit zeta"
FT                   /id="PRO_0000052854"
FT   BINDING         59
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   MOD_RES         1
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000269|PubMed:9342240"
FT   MOD_RES         38
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P02008"
FT   MOD_RES         53
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P02008"
FT   UNSURE          16
FT                   /note="K or R"
FT   UNSURE          17
FT                   /note="R or K"
FT   UNSURE          26
FT                   /note="K or R"
FT   UNSURE          43
FT                   /note="K or R"
FT   UNSURE          54
FT                   /note="K or R"
FT   UNSURE          71
FT                   /note="K or R"
FT   NON_CONS        16..17
FT                   /evidence="ECO:0000305"
FT   NON_CONS        42..43
FT                   /evidence="ECO:0000305"
FT   NON_TER         79
SQ   SEQUENCE   79 AA;  9185 MW;  5E61C3193F79C4B8 CRC64;
     SLTKTXXTII XAMWAKRLFT SYPQTKTYFP HFDLHPDSAQ LRKNIDNIHS ALSKLSELHA
     YILRVDPVNF KLLSHXFLV