AN32_PLAF7
ID AN32_PLAF7 Reviewed; 281 AA.
AC Q8ILI6; A0A144A431;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32-related protein;
DE AltName: Full=ANP32/acidic nuclear phosphoprotein-like protein;
GN ORFNames=PF14_0257, PF3D7_1427900;
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15895553; DOI=10.1080/14734220410019020;
RA Matilla A., Radrizzani M.;
RT "The Anp32 family of proteins containing leucine-rich repeats.";
RL Cerebellum 4:7-18(2005).
CC -!- SIMILARITY: Belongs to the ANP32 family. {ECO:0000305}.
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DR EMBL; LN999946; CZT99975.1; -; Genomic_DNA.
DR RefSeq; XP_001348431.1; XM_001348395.1.
DR AlphaFoldDB; Q8ILI6; -.
DR SMR; Q8ILI6; -.
DR BioGRID; 1207201; 5.
DR IntAct; Q8ILI6; 5.
DR STRING; 5833.PF14_0257; -.
DR PRIDE; Q8ILI6; -.
DR EnsemblProtists; CZT99975; CZT99975; PF3D7_1427900.
DR GeneID; 811839; -.
DR KEGG; pfa:PF3D7_1427900; -.
DR VEuPathDB; PlasmoDB:PF3D7_1427900; -.
DR HOGENOM; CLU_1006375_0_0_1; -.
DR InParanoid; Q8ILI6; -.
DR OMA; DKRSAFC; -.
DR PhylomeDB; Q8ILI6; -.
DR Proteomes; UP000001450; Chromosome 14.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR045081; AN32.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR11375; PTHR11375; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..281
FT /note="Acidic leucine-rich nuclear phosphoprotein 32-
FT related protein"
FT /id="PRO_0000240196"
FT REPEAT 29..52
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 56..78
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 79..103
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 105..128
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT DOMAIN 140..178
FT /note="LRRCT"
FT REGION 197..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..240
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..281
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 33006 MW; 432F43601A44F084 CRC64;
MEKAIRDRVE KWKKEHTIDG KDATNEHAYE SLNELILDGK KLTSIKNEEK ELLKNFKNLE
RLCLNQTGIQ TLENIPSIAT LNVLELTDNH LSSVEVLKYI VQNFPNIKTL EIGGNHFKNI
NDFETLKELK NLVRLGVQFN PFADNPNYRK ELFEFLPNVK IIDCYNKEGM EVLSSDEEEE
EEYEEDNTLK NFYEADFKDE DDEDEEFVPN DNEDDDEDDE LDDDLEDEDM EDLDKEDLDK
EDYDIDTKET EGVNKDEKSN KRKQDALDNT NDMDLKKTKL E