ID   HBB_COLGU               Reviewed;          41 AA.
AC   Q9TT33;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Hemoglobin subunit beta;
DE   AltName: Full=Beta-globin;
DE   AltName: Full=Hemoglobin beta chain;
DE   Flags: Fragment;
GN   Name=HBB;
OS   Colobus guereza (Mantled guereza) (Eastern black-and-white colobus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Colobinae; Colobus.
OX   NCBI_TaxID=33548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Blood;
RX   PubMed=10723742; DOI=10.1093/oxfordjournals.molbev.a026321;
RA   Francino M.P., Ochman H.;
RT   "Strand symmetry around the beta-globin origin of replication in
RT   primates.";
RL   Mol. Biol. Evol. 17:416-422(2000).
CC   -!- FUNCTION: Involved in oxygen transport from the lung to the various
CC       peripheral tissues.
CC   -!- SUBUNIT: Heterotetramer of two alpha chains and two beta chains.
CC   -!- TISSUE SPECIFICITY: Red blood cells.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   EMBL; AF205409; AAF23760.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9TT33; -.
DR   SMR; Q9TT33; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Heme; Iron; Metal-binding; Oxygen transport; Transport.
FT   CHAIN           <1..41
FT                   /note="Hemoglobin subunit beta"
FT                   /id="PRO_0000052931"
FT   MOD_RES         39
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P68871"
FT   NON_TER         1
SQ   SEQUENCE   41 AA;  4430 MW;  D00623EF0761B25B CRC64;
     LGNVLVCVLA HHFGKEFTPQ VQAAYQKVVA GVANALAHKY H