ID   AN36_HELPY              Reviewed;         329 AA.
AC   P94851;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=36 kDa antigen;
GN   OrderedLocusNames=HP_1488;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Hp921023;
RA   Hocking D., Rothel L., Doidge C., Radcliff F., Lee A., Webb E.;
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD08523.1; -; Genomic_DNA.
DR   EMBL; U86610; AAB81283.1; -; Genomic_DNA.
DR   PIR; H64705; H64705.
DR   RefSeq; NP_208279.1; NC_000915.1.
DR   RefSeq; WP_000071821.1; NC_018939.1.
DR   AlphaFoldDB; P94851; -.
DR   SMR; P94851; -.
DR   DIP; DIP-3275N; -.
DR   IntAct; P94851; 4.
DR   MINT; P94851; -.
DR   STRING; 85962.C694_07705; -.
DR   PaxDb; P94851; -.
DR   EnsemblBacteria; AAD08523; AAD08523; HP_1488.
DR   KEGG; hpy:HP_1488; -.
DR   PATRIC; fig|85962.47.peg.1599; -.
DR   eggNOG; COG0845; Bacteria.
DR   OMA; DAWAVFQ; -.
DR   PhylomeDB; P94851; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR032317; HlyD_D23.
DR   Pfam; PF16576; HlyD_D23; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..329
FT                   /note="36 kDa antigen"
FT                   /id="PRO_0000201861"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   VARIANT         67
FT                   /note="H -> R (in strain: Hp921023)"
FT   VARIANT         256
FT                   /note="E -> D (in strain: Hp921023)"
FT   VARIANT         272
FT                   /note="K -> R (in strain: Hp921023)"
FT   VARIANT         274
FT                   /note="T -> A (in strain: Hp921023)"
SQ   SEQUENCE   329 AA;  36199 MW;  B33A75727056DF87 CRC64;
     MSNSMLDKNK AILTGGGALL LGLIVLFYLA YRPKAEVLQG FLEAREYSVS SKVPGRIEKV
     FVKKGDHIKK GDLVFSISSP ELEAKLAQAE AGHKAAKALS DEVKRGSRDE TINSARDVWQ
     AAKSQATLAK ETYKRVQDLY DNGVASLQKR DEAYAAYEST KYNESAAYQK YKMALGGASS
     ESKIAAKAKE SAALGQVNEV ESYLKDVKAT APIDGEVSNV LLSGGELSPK GFPVVLMIDL
     KDSWLKISVP EKYLNEFKVG KEFEGYIPAL KKSTKFRVKY LSVMGDFATW KATNNSNTYD
     MKSYEVEAIP LEELENFRVG MSVLVTIKP