HBD_AILME
ID HBD_AILME Reviewed; 147 AA.
AC Q5XLE5;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Hemoglobin subunit delta;
DE AltName: Full=Delta-globin;
DE AltName: Full=Hemoglobin delta chain;
GN Name=HBD;
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA He P., Fang S.;
RT "Construction of the liver and brain cDNA libraries of the giant panda.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterotetramer of two delta chains and two alpha chains.
CC -!- TISSUE SPECIFICITY: Red blood cells.
CC -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00238}.
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DR EMBL; AY753986; AAV28721.1; -; mRNA.
DR RefSeq; NP_001291814.1; NM_001304885.1.
DR AlphaFoldDB; Q5XLE5; -.
DR SMR; Q5XLE5; -.
DR GeneID; 100499574; -.
DR KEGG; aml:100499574; -.
DR InParanoid; Q5XLE5; -.
DR OrthoDB; 1370439at2759; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd08925; Hb-beta-like; 1.
DR Gene3D; 1.10.490.10; -; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR002337; Hemoglobin_b.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00814; BETAHAEM.
DR SUPFAM; SSF46458; SSF46458; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 2: Evidence at transcript level;
KW Heme; Iron; Metal-binding; Oxygen transport; Reference proteome; Transport.
FT CHAIN 1..147
FT /note="Hemoglobin subunit delta"
FT /id="PRO_0000053160"
FT BINDING 64
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="distal binding residue"
FT BINDING 93
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="proximal binding residue"
SQ SEQUENCE 147 AA; 16181 MW; 2FA99C14CC404EB5 CRC64;
MVHLTGEEKA AVTGLWSKVN VDEVGGEALG RLLVVYPWTQ RFFDSFGDLS TPDAVMNNPK
VKAHGKKVLN SFSEGLKNLD NLKGTFVKLS ELHCDKLHVD PENFKLLGNV LVCVLAHHFG
KEFTPQVQAA YQKVVAGVAN ALAHKYH