位置:首页 > 蛋白库 > HBD_CARSF
HBD_CARSF
ID   HBD_CARSF               Reviewed;         147 AA.
AC   P13558;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Hemoglobin subunit delta;
DE   AltName: Full=Delta-globin;
DE   AltName: Full=Hemoglobin delta chain;
GN   Name=HBD;
OS   Carlito syrichta (Philippine tarsier) (Tarsius syrichta).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Tarsiiformes; Tarsiidae;
OC   Carlito.
OX   NCBI_TaxID=1868482;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2491855; DOI=10.1016/s0021-9258(17)31225-5;
RA   Koop B.F., Siemieniak D., Slightom J.L., Goodman M., Dunbar J.,
RA   Wright P.C., Simons E.L.;
RT   "Tarsius delta- and beta-globin genes: conversions, evolution, and
RT   systematic implications.";
RL   J. Biol. Chem. 264:68-79(1989).
CC   -!- SUBUNIT: Heterotetramer of two delta chains and two alpha chains.
CC   -!- TISSUE SPECIFICITY: Red blood cells.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; J04428; AAA36957.1; -; Genomic_DNA.
DR   RefSeq; XP_008050891.1; XM_008052700.1.
DR   AlphaFoldDB; P13558; -.
DR   SMR; P13558; -.
DR   STRING; 1868482.ENSTSYP00000002520; -.
DR   GeneID; 103254683; -.
DR   KEGG; csyr:103254683; -.
DR   HOGENOM; CLU_003827_10_0_1; -.
DR   OMA; TPDAVMN; -.
DR   OrthoDB; 1370439at2759; -.
DR   TreeFam; TF333268; -.
DR   Proteomes; UP000189704; Unplaced.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd08925; Hb-beta-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR002337; Hemoglobin_b.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00814; BETAHAEM.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Oxygen transport; Reference proteome; Transport.
FT   CHAIN           1..147
FT                   /note="Hemoglobin subunit delta"
FT                   /id="PRO_0000053174"
FT   BINDING         64
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT   BINDING         93
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
SQ   SEQUENCE   147 AA;  16022 MW;  B14E2EEE3D5368DD CRC64;
     MVHLTADEKA AVTALWSKVN VEDVGGEALG RLLVVYPWTQ RFFDSFGDLS TPAAVMSNAK
     VKAHGKKVLN AFSDGMAHLD NLKGTFAKLS ELHCDKLHVD PENFRLLGNV LVCVLAHHFG
     KQFTPQLQAA YQKVVAGVAA ALAHKYH
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024