HBD_SAGMY
ID HBD_SAGMY Reviewed; 146 AA.
AC P68014; P02045;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Hemoglobin subunit delta;
DE AltName: Full=Delta-globin;
DE AltName: Full=Hemoglobin delta chain;
GN Name=HBD;
OS Saguinus mystax (Moustached tamarin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Saguinus.
OX NCBI_TaxID=9488;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=4999925; DOI=10.1007/bf00487132;
RA Boyer S.H., Crosby E.F., Noyes A.N., Fuller G.F., Leslie S.E.,
RA Donaldson L.J., Vrablik G.R., Schaefer E.W. Jr., Thurmon T.F.;
RT "Primate hemoglobins: some sequences and some proposals concerning the
RT character of evolution and mutation.";
RL Biochem. Genet. 5:405-448(1971).
CC -!- SUBUNIT: Heterotetramer of two delta chains and two alpha chains.
CC -!- TISSUE SPECIFICITY: Red blood cells.
CC -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00238}.
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DR PIR; D02365; HDMKTM.
DR AlphaFoldDB; P68014; -.
DR SMR; P68014; -.
DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd08925; Hb-beta-like; 1.
DR Gene3D; 1.10.490.10; -; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR002337; Hemoglobin_b.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00814; BETAHAEM.
DR SUPFAM; SSF46458; SSF46458; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport;
KW Phosphoprotein; Transport.
FT CHAIN 1..146
FT /note="Hemoglobin subunit delta"
FT /id="PRO_0000053171"
FT BINDING 63
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="distal binding residue"
FT BINDING 92
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="proximal binding residue"
FT MOD_RES 50
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P02042"
FT UNSURE 12
FT /note="A or S"
FT UNSURE 16
FT /note="S or G"
SQ SEQUENCE 146 AA; 15808 MW; 12174F1345B7BD80 CRC64;
VHLTGDEKSA VAALWSKVNV DEVGGEALGR LLVVYPWTQR FFESFGALSS PDAVMGNPKV
KAHGKKVLGA FSDGLAHLDN LKGTFAQLSE LHCDKLHVDP ENFRLLGNVL VCVLARNFGK
EFTPRVQAAF QKVVAGVATA LAHKYH