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HBD_SAGMY
ID   HBD_SAGMY               Reviewed;         146 AA.
AC   P68014; P02045;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Hemoglobin subunit delta;
DE   AltName: Full=Delta-globin;
DE   AltName: Full=Hemoglobin delta chain;
GN   Name=HBD;
OS   Saguinus mystax (Moustached tamarin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Saguinus.
OX   NCBI_TaxID=9488;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=4999925; DOI=10.1007/bf00487132;
RA   Boyer S.H., Crosby E.F., Noyes A.N., Fuller G.F., Leslie S.E.,
RA   Donaldson L.J., Vrablik G.R., Schaefer E.W. Jr., Thurmon T.F.;
RT   "Primate hemoglobins: some sequences and some proposals concerning the
RT   character of evolution and mutation.";
RL   Biochem. Genet. 5:405-448(1971).
CC   -!- SUBUNIT: Heterotetramer of two delta chains and two alpha chains.
CC   -!- TISSUE SPECIFICITY: Red blood cells.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; D02365; HDMKTM.
DR   AlphaFoldDB; P68014; -.
DR   SMR; P68014; -.
DR   GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd08925; Hb-beta-like; 1.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR002337; Hemoglobin_b.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00814; BETAHAEM.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding; Oxygen transport;
KW   Phosphoprotein; Transport.
FT   CHAIN           1..146
FT                   /note="Hemoglobin subunit delta"
FT                   /id="PRO_0000053171"
FT   BINDING         63
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT   BINDING         92
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT   MOD_RES         50
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P02042"
FT   UNSURE          12
FT                   /note="A or S"
FT   UNSURE          16
FT                   /note="S or G"
SQ   SEQUENCE   146 AA;  15808 MW;  12174F1345B7BD80 CRC64;
     VHLTGDEKSA VAALWSKVNV DEVGGEALGR LLVVYPWTQR FFESFGALSS PDAVMGNPKV
     KAHGKKVLGA FSDGLAHLDN LKGTFAQLSE LHCDKLHVDP ENFRLLGNVL VCVLARNFGK
     EFTPRVQAAF QKVVAGVATA LAHKYH
 
 
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