HBEAG_HBVB3
ID HBEAG_HBVB3 Reviewed; 27 AA.
AC P0C6G8;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 1.
DT 29-SEP-2021, entry version 18.
DE RecName: Full=Truncated HBeAg protein;
GN Name=C;
OS Hepatitis B virus genotype B2 (isolate Vietnam/9873/1997) (HBV-B).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=489461;
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10640544; DOI=10.1099/0022-1317-81-1-75;
RA Hannoun C., Horal P., Lindh M.;
RT "Long-term mutation rates in the hepatitis B virus genome.";
RL J. Gen. Virol. 81:75-83(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Isolate BAJT2006-1C, and Isolate BAJT2006-1S;
RA Inoue J., Ueno Y., Kogure T., Nagasaki F., Kimura O., Obara N., Kido O.,
RA Nakagome Y., Kakazu E., Matsuda Y., Fukushima K., Segawa H., Nakajima I.,
RA Itoyama Y., Takahashi M., Okamoto H., Shimosegawa T.;
RT "Sequence analysis of hepatitis B virus in the cerebrospinal fluid of a
RT patient with acute hepatitits B following acute onset of transverse
RT myelitis.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=External core antigen;
CC IsoId=P0C6G8-1; Sequence=Displayed;
CC Name=Capsid protein;
CC IsoId=Q9QAB9-1; Sequence=External;
CC -!- MISCELLANEOUS: This virus has been isolated from a low active healthy
CC carrier of HBV, negative for HBeAg. A genomic mutation in 1896 creates
CC a stop codon at position 28 of HBeAg, without affecting capsid open
CC reading frame. The HBeAg negative variants of HBV are associated with
CC fulminant hepatitis, but can also be found in patients with persistent
CC infection and chronic hepatitis.
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DR EMBL; AF121251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AB298720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AB298721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Proteomes; UP000007915; Genome.
DR Proteomes; UP000154547; Genome.
DR Proteomes; UP000159572; Genome.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR InterPro; IPR013195; Hepatitis_B_virus_capsid_N.
DR Pfam; PF08290; Hep_core_N; 1.
PE 4: Predicted;
KW Alternative initiation.
FT CHAIN 1..27
FT /note="Truncated HBeAg protein"
FT /id="PRO_0000324706"
SQ SEQUENCE 27 AA; 3009 MW; B42B8A7F1C7B689D CRC64;
MQLFHLCLII SCSCPTVQAS KLCLGWL