HBEAG_HBVB6
ID HBEAG_HBVB6 Reviewed; 27 AA.
AC P0C6H0; Q76QH2;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 1.
DT 29-SEP-2021, entry version 21.
DE RecName: Full=Truncated HBeAg protein;
GN Name=C;
OS Hepatitis B virus genotype B2 subtype adw (isolate China/patient4/1996)
OS (HBV-B).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=489463;
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8871878; DOI=10.1111/j.1365-2893.1996.tb00092.x;
RA Alexopoulou A., Karayiannis P., Hadziyannis S.J.;
RT "Whole genome analysis of hepatitis B virus from four cases of fulminant
RT hepatitis: genetic variability and its potential role in disease
RT pathogenicity.";
RL J. Viral Hepat. 3:173-181(1996).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=External core antigen;
CC IsoId=P0C6H0-1; Sequence=Displayed;
CC Name=Capsid protein;
CC IsoId=Q67924-1; Sequence=External;
CC -!- MISCELLANEOUS: This virus has been isolated from a patient with
CC fulminant hepatitis. A genomic mutation in 1898 creates a stop codon at
CC position 28 of HBeAg, without affecting the capsid open reading frame.
CC The HBeAg negative variants of HBV are associated with fulminant
CC hepatitis, but can also be found in patients with persistent infection
CC and chronic hepatitis.
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DR EMBL; X97850; CAA66439.1; -; Genomic_DNA.
DR Proteomes; UP000007917; Genome.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR InterPro; IPR013195; Hepatitis_B_virus_capsid_N.
DR Pfam; PF08290; Hep_core_N; 1.
PE 4: Predicted;
KW Alternative initiation.
FT CHAIN 1..27
FT /note="Truncated HBeAg protein"
FT /id="PRO_0000324709"
SQ SEQUENCE 27 AA; 3009 MW; B42B8A7F1C7B689D CRC64;
MQLFHLCLII SCSCPTVQAS KLCLGWL