HBEAG_HBVB8
ID HBEAG_HBVB8 Reviewed; 27 AA.
AC P0C6K6;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 1.
DT 29-SEP-2021, entry version 18.
DE RecName: Full=Truncated HBeAg protein;
GN Name=C;
OS Hepatitis B virus genotype B1 (isolate Japan/Ry30/2002) (HBV-B).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=489465;
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=12021331; DOI=10.1128/jvi.76.12.5985-5992.2002;
RA Sugauchi F., Orito E., Ichida T., Kato H., Sakugawa H., Kakumu S.,
RA Ishida T., Chutaputti A., Lai C.L., Ueda R., Miyakawa Y., Mizokami M.;
RT "Hepatitis B virus of genotype B with or without recombination with
RT genotype C over the precore region plus the core gene.";
RL J. Virol. 76:5985-5992(2002).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=External core antigen;
CC IsoId=P0C6K6-1; Sequence=Displayed;
CC Name=Capsid protein;
CC IsoId=P0C677-1; Sequence=External;
CC -!- MISCELLANEOUS: A genomic mutation in 1896 creates a stop codon at
CC position 28 of HBeAg, without affecting capsid open reading frame. The
CC HBeAg negative variants of HBV are associated with fulminant hepatitis,
CC but can also be found in patients with persistent infection and chronic
CC hepatitis.
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DR EMBL; AB073854; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Proteomes; UP000007919; Genome.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR InterPro; IPR013195; Hepatitis_B_virus_capsid_N.
DR Pfam; PF08290; Hep_core_N; 1.
PE 4: Predicted;
KW Alternative initiation.
FT CHAIN 1..27
FT /note="Truncated HBeAg protein"
FT /id="PRO_0000324711"
SQ SEQUENCE 27 AA; 2995 MW; B42B9C13CC7B689D CRC64;
MQLFHLCLVI SCSCPTVQAS KLCLGWL