HBEAG_HBVC9
ID HBEAG_HBVC9 Reviewed; 27 AA.
AC P0C6K5;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 1.
DT 25-MAY-2022, entry version 19.
DE RecName: Full=Truncated HBeAg protein;
GN Name=C;
OS Hepatitis B virus genotype C subtype ayw (isolate Australia/AustRC/1992)
OS (HBV-C).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus;
OC hepatitis B virus genotype C.
OX NCBI_TaxID=489471;
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11257194; DOI=10.1099/0022-1317-82-4-883;
RA Sugauchi F., Mizokami M., Orito E., Ohno T., Kato H., Suzuki S., Kimura Y.,
RA Ueda R., Butterworth L.A., Cooksley W.G.;
RT "A novel variant genotype C of hepatitis B virus identified in isolates
RT from Australian Aborigines: complete genome sequence and phylogenetic
RT relatedness.";
RL J. Gen. Virol. 82:883-892(2001).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=External core antigen;
CC IsoId=P0C6K5-1; Sequence=Displayed;
CC Name=Capsid protein;
CC IsoId=P0C6H8-1; Sequence=External;
CC -!- MISCELLANEOUS: This virus has been isolated from patient with fulminant
CC hepatitis. A genomic mutation in 1896 creates a stop codon at position
CC 28 of HBeAg, without affecting capsid open reading frame. The HBeAg
CC negative variants of HBV are associated with fulminant hepatitis, but
CC can also be found in patients with persistent infection and chronic
CC hepatitis.
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DR EMBL; AB048704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Proteomes; UP000007927; Genome.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR InterPro; IPR013195; Hepatitis_B_virus_capsid_N.
DR Pfam; PF08290; Hep_core_N; 1.
PE 4: Predicted;
KW Alternative initiation.
FT CHAIN 1..27
FT /note="Truncated HBeAg protein"
FT /id="PRO_0000324722"
SQ SEQUENCE 27 AA; 3009 MW; B42B8A7F1C7B689D CRC64;
MQLFHLCLII SCSCPTVQAS KLCLGWL