ID   AND1A_MACFA             Reviewed;         471 AA.
AC   Q9GKW8;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-FEB-2010, sequence version 3.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Ankyrin repeat and death domain-containing protein 1A;
DE   Flags: Fragment;
GN   Name=ANKDD1A; ORFNames=QccE-18247;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RX   PubMed=11574149; DOI=10.1016/s0378-1119(01)00665-5;
RA   Osada N., Hida M., Kususda J., Tanuma R., Iseki K., Hirata M., Suto Y.,
RA   Hirai M., Terao K., Suzuki Y., Sugano S., Hashimoto K.;
RT   "Assignment of 118 novel cDNAs of cynomolgus monkey brain to human
RT   chromosomes.";
RL   Gene 275:31-37(2001).
RN   [2]
RP   ERRATUM OF PUBMED:11574149.
RA   Osada N., Hida M., Kusuda J., Tanuma R., Iseki K., Hirata M., Suto Y.,
RA   Hirai M., Terao K., Suzuki Y., Sugano S., Hashimoto K., Kususda J.;
RL   Gene 278:267-267(2001).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB18137.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AB051111; BAB18137.1; ALT_FRAME; mRNA.
DR   AlphaFoldDB; Q9GKW8; -.
DR   SMR; Q9GKW8; -.
DR   eggNOG; KOG4177; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.533.10; -; 1.
DR   Gene3D; 1.25.40.20; -; 4.
DR   InterPro; IPR039194; AKD1A.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   PANTHER; PTHR24125:SF0; PTHR24125:SF0; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   Pfam; PF13637; Ank_4; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 10.
DR   SUPFAM; SSF47986; SSF47986; 1.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 8.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           <1..471
FT                   /note="Ankyrin repeat and death domain-containing protein
FT                   1A"
FT                   /id="PRO_0000287883"
FT   REPEAT          19..48
FT                   /note="ANK 1"
FT   REPEAT          52..81
FT                   /note="ANK 2"
FT   REPEAT          85..114
FT                   /note="ANK 3"
FT   REPEAT          120..149
FT                   /note="ANK 4"
FT   REPEAT          153..182
FT                   /note="ANK 5"
FT   REPEAT          186..215
FT                   /note="ANK 6"
FT   REPEAT          219..248
FT                   /note="ANK 7"
FT   REPEAT          251..280
FT                   /note="ANK 8"
FT   REPEAT          284..313
FT                   /note="ANK 9"
FT   REPEAT          317..346
FT                   /note="ANK 10"
FT   DOMAIN          379..467
FT                   /note="Death"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00064"
FT   NON_TER         1
SQ   SEQUENCE   471 AA;  51599 MW;  882EC33755649F29 CRC64;
     RGCGTAGCRR TWRGRPTAVG RVALHWAAGA GHEQAVRLLL EHEAAVDEED AFGMNALLLS
     AWFGHLRILQ ILVNSGAKIH CKSKDGLTLL HCAAQKGHVP VLAFIMEDLE DVALDHVDKL
     GRTAFHRAAE HGQLDALDFL VGSGCDHSVK DKEGNTALHL AAGRGHMAVL QRLVDIGLDL
     EEQNAEGLTA LHAAAGGTHP HCVRLLLRAG STVNALTQKN LSCLHYAALS GSEDVSRVLI
     HAGGCTNVAD HGASPLHLAV MHNFPALVQL LINSDSDLNA MDNRQQTPLH LAAEHAWQDI
     AEMLLIAGVD LNLRDKQGKT ALAVAARSNH VSLVDMIIKA DRFYKWEKDH LSCRDLSDPS
     GKSLSFKQDH RQETQQLRSV LWRLASRHLQ PREWKKLAYS WDFTEAHVYA IEQQWTGTRS
     YQEHGHRMLL IWLHGVSTAG ENPSKALFEG LVTIGRRDLA ELAVASVGAY I