ID   HBHA_MYCLE              Reviewed;         188 AA.
AC   Q9CB42;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Heparin-binding hemagglutinin homolog;
DE   AltName: Full=Adhesin;
GN   Name=hbhA; OrderedLocusNames=ML2454;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: Might mediate adherence to host cells by binding sulfated
CC       glycoconjugates.
CC   -!- SIMILARITY: To M.tuberculosis HbhA. {ECO:0000305}.
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DR   EMBL; AL583925; CAC31971.1; -; Genomic_DNA.
DR   PIR; C87216; C87216.
DR   RefSeq; NP_302592.1; NC_002677.1.
DR   RefSeq; WP_010908911.1; NC_002677.1.
DR   AlphaFoldDB; Q9CB42; -.
DR   SMR; Q9CB42; -.
DR   STRING; 272631.ML2454; -.
DR   EnsemblBacteria; CAC31971; CAC31971; CAC31971.
DR   KEGG; mle:ML2454; -.
DR   PATRIC; fig|272631.5.peg.4708; -.
DR   Leproma; ML2454; -.
DR   eggNOG; ENOG50335M1; Bacteria.
DR   HOGENOM; CLU_089817_1_0_11; -.
DR   OMA; RERWANL; -.
DR   Proteomes; UP000000806; Chromosome.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..188
FT                   /note="Heparin-binding hemagglutinin homolog"
FT                   /id="PRO_0000083909"
FT   REGION          162..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..188
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   188 AA;  20421 MW;  CB8DF064C675D9B8 CRC64;
     MAENPNVDDL RAPLLAALGA ADLALTTVNE LVGNMRERAE ETRIDTRSRV EESRARVAKL
     QEVLPEHLSE LREKFTADEL RKAAEGYLEA ATNRYNELVE RGEAALERLR SRPVFEDASA
     RAEGYVDQAV ELTQEALGTV ASQTRAVGGR AAKLVGIELP KKAAAPARKA PAKKAPAKKA
     PAKKVTQK