ID   HBL_TRETO               Reviewed;         161 AA.
AC   P07803;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Non-symbiotic hemoglobin;
DE   AltName: Full=TREto GLB1;
GN   Name=GLB1;
OS   Trema tomentosa (Peach-leaf poison-bush) (Celtis tomentosa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Cannabaceae; Trema.
OX   NCBI_TaxID=3480;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2448639; DOI=10.1038/331178a0;
RA   Bogusz D., Appleby C.A., Landsmann J., Dennis E.S., Trinick M.J.,
RA   Peacock W.J.;
RT   "Functioning haemoglobin genes in non-nodulating plants.";
RL   Nature 331:178-180(1988).
CC   -!- FUNCTION: May not function as an oxygen storage or transport protein,
CC       but might act as an oxygen sensor or play a role in electron transfer,
CC       possibly to a bound oxygen molecule.
CC   -!- SUBUNIT: Homodimer.
CC   -!- TISSUE SPECIFICITY: Root specific.
CC   -!- SIMILARITY: Belongs to the plant globin family. {ECO:0000305}.
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DR   EMBL; Y00296; CAA68405.1; -; Genomic_DNA.
DR   PIR; S00838; S00838.
DR   PDB; 3QQQ; X-ray; 1.84 A; A/B=1-161.
DR   PDBsum; 3QQQ; -.
DR   AlphaFoldDB; P07803; -.
DR   SMR; P07803; -.
DR   EvolutionaryTrace; P07803; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR001032; Leghaemoglobin.
DR   InterPro; IPR019824; Leghaemoglobin_Fe_BS.
DR   PANTHER; PTHR22924; PTHR22924; 1.
DR   Pfam; PF00042; Globin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
DR   PROSITE; PS00208; PLANT_GLOBIN; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Heme; Iron; Metal-binding.
FT   CHAIN           1..161
FT                   /note="Non-symbiotic hemoglobin"
FT                   /id="PRO_0000193026"
FT   BINDING         70
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         105
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   HELIX           12..25
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           26..28
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           29..43
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           45..50
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           52..54
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           61..63
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           67..87
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           95..107
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           112..128
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   TURN            130..132
FT                   /evidence="ECO:0007829|PDB:3QQQ"
FT   HELIX           135..154
FT                   /evidence="ECO:0007829|PDB:3QQQ"
SQ   SEQUENCE   161 AA;  18150 MW;  5CFDD6EB116DD6D4 CRC64;
     MSSSEVDKVF TEEQEALVVK SWAVMKKNSA ELGLKFFLKI FEIAPSAKNL FSYLKDSPIP
     LEQNPKLKPH AMTVFVMTCE SAVQLRKAGK VTVRESNLKR LGAIHFKNGV VNEHFETRFA
     LLETIKEAVP EMWSPEMKNA WGEAYDQLVA AIKSEMKPSS T