ID   HBPA_CASGL              Reviewed;         152 AA.
AC   Q42665;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Hemoglobin A;
GN   Name=SYMA;
OS   Casuarina glauca (Swamp oak).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fagales; Casuarinaceae; Casuarina.
OX   NCBI_TaxID=3522;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Root nodule;
RA   Jacobbsen-Lyon K., Dennis E.S., Jensen E.O., Marcker K.A., Peacock W.P.;
RT   "Symbiotic haemoglobin genes of the Casuarina-Frankia actinorhizal
RT   symbiosis.";
RL   Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Provides oxygen to the bacteroids. This role is essential for
CC       symbiotic nitrogen fixation (By similarity). {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Root nodules.
CC   -!- SIMILARITY: Belongs to the plant globin family. {ECO:0000305}.
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DR   EMBL; X77694; CAA54774.1; -; mRNA.
DR   PIR; S42044; S42044.
DR   AlphaFoldDB; Q42665; -.
DR   SMR; Q42665; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.490.10; -; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR001032; Leghaemoglobin.
DR   InterPro; IPR019824; Leghaemoglobin_Fe_BS.
DR   PANTHER; PTHR22924; PTHR22924; 1.
DR   Pfam; PF00042; Globin; 1.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
DR   PROSITE; PS00208; PLANT_GLOBIN; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Nitrogen fixation; Oxygen transport; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..152
FT                   /note="Hemoglobin A"
FT                   /id="PRO_0000192979"
FT   BINDING         63
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
FT   BINDING         98
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00238"
SQ   SEQUENCE   152 AA;  17209 MW;  0F59BEE4919BD78A CRC64;
     MALTERQEAL LKQSWEVLKQ NIPGHSLRLF ALIIEAAPES KYVFSFLKDS NEIPENNPKL
     KAHAAVIFKT ICESATELRQ KGQAVWDNNT LKRLGSIHLK NKITDPHFEV MKGALLGTIK
     EAVKENWSDE MGCAWTEAYN QLVATIKAEM KE