ID   HCT2_CHLMU              Reviewed;         207 AA.
AC   P38020;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Histone H1-like protein HC2;
DE   AltName: Full=HC2 nucleoprotein;
DE   AltName: Full=Histone H1-like protein KARP;
GN   Name=hctB; Synonyms=karP; OrderedLocusNames=TC_0316;
OS   Chlamydia muridarum (strain MoPn / Nigg).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=243161;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MoPn;
RX   PubMed=1549572; DOI=10.1073/pnas.89.6.2125;
RA   Perara E., Ganem D., Engel J.N.;
RT   "A developmentally regulated chlamydial gene with apparent homology to
RT   eukaryotic histone H1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:2125-2129(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MoPn / Nigg;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
CC   -!- FUNCTION: Might have a role in establishing the nucleoid structure of
CC       elementary bodies.
CC   -!- DEVELOPMENTAL STAGE: Expressed late in chlamydial development, during
CC       the transition from reticulate bodies to elementary bodies.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. HCT subfamily.
CC       {ECO:0000305}.
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DR   EMBL; M86605; AAA73195.1; -; Genomic_DNA.
DR   EMBL; AE002160; AAF39181.1; -; Genomic_DNA.
DR   PIR; G81715; G81715.
DR   RefSeq; WP_010232112.1; NC_002620.2.
DR   AlphaFoldDB; P38020; -.
DR   STRING; 243161.TC_0316; -.
DR   EnsemblBacteria; AAF39181; AAF39181; TC_0316.
DR   GeneID; 1246359; -.
DR   KEGG; cmu:TC_0316; -.
DR   eggNOG; ENOG50335M1; Bacteria.
DR   HOGENOM; CLU_101293_0_0_0; -.
DR   OMA; CKRVCSS; -.
DR   OrthoDB; 2064190at2; -.
DR   Proteomes; UP000000800; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR   InterPro; IPR009970; HC2.
DR   Pfam; PF07382; HC2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Repeat.
FT   CHAIN           1..207
FT                   /note="Histone H1-like protein HC2"
FT                   /id="PRO_0000196020"
FT   REPEAT          35..58
FT                   /note="1"
FT   REPEAT          71..94
FT                   /note="2"
FT   REPEAT          113..136
FT                   /note="3"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          35..136
FT                   /note="3 X 24 AA repeats of V-R-K-V-A-A-K-K-T-V-A-R-K-T-V-
FT                   A-K-K-A-V-A-A-R-K"
FT   COMPBIAS        9..72
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   207 AA;  21982 MW;  E549637BBA768FF0 CRC64;
     MLGVQKKRST RKTAARKTVV RKPAAKKTAA KKASVRKVAA KKTVARKTVA KKAVAARKPA
     AKKTAAKKAP VRKVAAKKTV ARKTVAKKAV AARKTVAKKS VAARKTAAKK APVRKVAAKK
     TVARKTVAKK AVAARKPAAK RTVSTKKTAV AAKAGVCMKK HKHTAACGRV AASGVKVCAS
     SAKRRTHHNR SRTAHSWRQQ LMKLVAK