ID   HD10_ENCCU              Reviewed;         227 AA.
AC   Q8SW18; Q7SI88;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Homeobox protein HD-10;
DE   AltName: Full=EcHD-10;
GN   Name=HD-10; OrderedLocusNames=ECU03_1170;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   DISCUSSION OF SEQUENCE.
RX   PubMed=12590353; DOI=10.1007/s00427-002-0287-3;
RA   Buerglin T.R.;
RT   "The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a
RT   putative mating-type locus.";
RL   Dev. Genes Evol. 213:50-52(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   EMBL; AL590443; CAD26261.1; -; Genomic_DNA.
DR   EMBL; BK001341; DAA01304.1; -; Genomic_DNA.
DR   RefSeq; NP_597626.1; NM_001040990.1.
DR   AlphaFoldDB; Q8SW18; -.
DR   SMR; Q8SW18; -.
DR   GeneID; 858788; -.
DR   KEGG; ecu:ECU03_1170; -.
DR   VEuPathDB; MicrosporidiaDB:ECU03_1170; -.
DR   HOGENOM; CLU_106359_0_0_1; -.
DR   InParanoid; Q8SW18; -.
DR   OrthoDB; 1214016at2759; -.
DR   Proteomes; UP000000819; Chromosome III.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           1..227
FT                   /note="Homeobox protein HD-10"
FT                   /id="PRO_0000048919"
FT   DNA_BIND        30..89
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          88..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..115
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   227 AA;  26688 MW;  F887B2CB195C73AC CRC64;
     MDNFGGNFFN SYSNNSNREV EGNQYFDPYF VKHRKRTTKA QLKVLEETFE TNIRPDANMR
     KKLGEQLGMT PRSVQVWFQN RRAKIKKLTQ KKMMQQENTD NTKGPDAAHG SSSPKECKYN
     SYYPYIPIQG PLEEFNVYPR DNSIYKHGMP QGMASPIMYE GFGYRGHEEY GYPYVQRYGG
     GEYYQMQYPY GMVQAQWHQP PGFRDDDYYH SARKQQYRGG APNSEKM