ID   HD6N_ORYSJ              Reviewed;          90 AA.
AC   Q9AQU1; C7J070; Q10EU1; Q94H91;
DT   05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Inactive casein kinase II subunit alpha-2 {ECO:0000305};
DE            Short=OsCKA2 {ECO:0000305};
DE   AltName: Full=Protein HEADING DATE 6 {ECO:0000303|PubMed:11416158};
GN   Name=HD6 {ECO:0000303|PubMed:11416158}; Synonyms=CKA2 {ECO:0000305};
GN   OrderedLocusNames=Os03g0762000 {ECO:0000312|EMBL:BAS86517.1},
GN   LOC_Os03g55389 {ECO:0000312|EMBL:ABF99014.1};
GN   ORFNames=OSJNBb0048A17.1 {ECO:0000312|EMBL:AAK63938.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND FUNCTION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=11416158; DOI=10.1073/pnas.111136798;
RA   Takahashi Y., Shomura A., Sasaki T., Yano M.;
RT   "Hd6, a rice quantitative trait locus involved in photoperiod sensitivity,
RT   encodes the alpha subunit of protein kinase CK2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7922-7927(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [5]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: The Nipponbare allele of HD6 contains a premature stop codon,
CC       resulting in a truncated non-functional product.
CC       {ECO:0000269|PubMed:11416158}.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC       kinase family. CK2 subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK63938.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=ABF99014.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAH92378.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAS86516.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AB036785; BAB21588.1; -; Genomic_DNA.
DR   EMBL; AB036787; BAB21590.1; -; mRNA.
DR   EMBL; AC084282; AAK63938.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000009; ABF99014.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008209; BAH92378.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014959; BAS86516.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014959; BAS86517.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9AQU1; -.
DR   SMR; Q9AQU1; -.
DR   STRING; 4530.OS03T0762000-01; -.
DR   PRIDE; Q9AQU1; -.
DR   EnsemblPlants; Os03t0762000-02; Os03t0762000-02; Os03g0762000.
DR   Gramene; Os03t0762000-02; Os03t0762000-02; Os03g0762000.
DR   eggNOG; KOG0668; Eukaryota.
DR   HOGENOM; CLU_000288_70_2_1; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005956; C:protein kinase CK2 complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0010229; P:inflorescence development; IMP:Gramene.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IBA:GO_Central.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IBA:GO_Central.
DR   GO; GO:0009648; P:photoperiodism; IMP:Gramene.
DR   GO; GO:0051726; P:regulation of cell cycle; IBA:GO_Central.
DR   InterPro; IPR045216; CK2_alpha.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   PANTHER; PTHR24054; PTHR24054; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..90
FT                   /note="Inactive casein kinase II subunit alpha-2"
FT                   /id="PRO_0000437454"
FT   BINDING         40..48
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   BINDING         63
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
SQ   SEQUENCE   90 AA;  10498 MW;  F63D1DF20BC52CEF CRC64;
     MSKARVYADV NVLRPKEYWD YEALTVQWGE QDDYEVVRKV GRGKYSEVFE GINVNNNEKC
     IIKILKPVKK KKIKREIKIL QNLCGGPNIV