ID   HD6_ENCCU               Reviewed;         121 AA.
AC   Q8SVT6; Q7SI85;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Homeobox protein HD-6;
DE   AltName: Full=EcHD-6;
GN   Name=HD-6; OrderedLocusNames=ECU04_0970;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   DISCUSSION OF SEQUENCE.
RX   PubMed=12590353; DOI=10.1007/s00427-002-0287-3;
RA   Buerglin T.R.;
RT   "The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a
RT   putative mating-type locus.";
RL   Dev. Genes Evol. 213:50-52(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus.
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DR   EMBL; AL590444; CAD25284.1; -; Genomic_DNA.
DR   EMBL; BK001344; DAA01307.1; -; Genomic_DNA.
DR   RefSeq; NP_584780.1; NM_001041130.1.
DR   AlphaFoldDB; Q8SVT6; -.
DR   SMR; Q8SVT6; -.
DR   GeneID; 858928; -.
DR   KEGG; ecu:ECU04_0970; -.
DR   VEuPathDB; MicrosporidiaDB:ECU04_0970; -.
DR   HOGENOM; CLU_166290_0_0_1; -.
DR   InParanoid; Q8SVT6; -.
DR   OrthoDB; 1486405at2759; -.
DR   Proteomes; UP000000819; Chromosome IV.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           1..121
FT                   /note="Homeobox protein HD-6"
FT                   /id="PRO_0000048915"
FT   DNA_BIND        28..87
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
SQ   SEQUENCE   121 AA;  14972 MW;  D1BE94AC27134069 CRC64;
     MTNGRKMEYK LVDSEKDIER SYEPRRKPKR SRIQLHDWQS MLLEHSFRMN PYPDRIEKYN
     LFLKTKIPMK NVKIWFQNRR AREKSFYEEA VEVHRDGRRA GHRSLGSRSA LFAEEFQYRR
     Y