ID   HD7_ENCCU               Reviewed;         107 AA.
AC   Q8SW50; Q7SI89;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2013, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Homeobox protein HD-7;
DE   AltName: Full=EcHD-7;
GN   Name=HD-7; OrderedLocusNames=ECU03_0610;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GB-M1;
RX   PubMed=20003517; DOI=10.1186/1471-2164-10-607;
RA   Peyretaillade E., Goncalves O., Terrat S., Dugat-Bony E., Wincker P.,
RA   Cornman R.S., Evans J.D., Delbac F., Peyret P.;
RT   "Identification of transcriptional signals in Encephalitozoon cuniculi
RT   widespread among Microsporidia phylum: support for accurate structural
RT   genome annotation.";
RL   BMC Genomics 10:607-607(2009).
RN   [3]
RP   GENE NAME.
RX   PubMed=12590353; DOI=10.1007/s00427-002-0287-3;
RA   Buerglin T.R.;
RT   "The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a
RT   putative mating-type locus.";
RL   Dev. Genes Evol. 213:50-52(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=DAA01303.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL590443; CAD26207.2; -; Genomic_DNA.
DR   EMBL; BK001340; DAA01303.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_597572.1; NM_001040936.1.
DR   AlphaFoldDB; Q8SW50; -.
DR   SMR; Q8SW50; -.
DR   GeneID; 858734; -.
DR   KEGG; ecu:ECU03_0610; -.
DR   VEuPathDB; MicrosporidiaDB:ECU03_0610; -.
DR   HOGENOM; CLU_128308_1_0_1; -.
DR   InParanoid; Q8SW50; -.
DR   OrthoDB; 1529443at2759; -.
DR   Proteomes; UP000000819; Chromosome III.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           1..107
FT                   /note="Homeobox protein HD-7"
FT                   /id="PRO_0000048916"
FT   DNA_BIND        21..80
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
SQ   SEQUENCE   107 AA;  12386 MW;  3ECCF2F10755F28A CRC64;
     MEVQAVLGMI LLFHPERCSK KPGEKVRKSE FQKEVLKKVY QATPYPTWEN KIDIGILISL
     SPRAVDIWFQ NKRHINKGKN QGVDEAVESR TIDLQTIMSI VESTLRY