ID   HDED_ECO57              Reviewed;         190 AA.
AC   P0AET6; P26603; P28326;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Protein HdeD;
GN   Name=hdeD; OrderedLocusNames=Z4923, ECs4391;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
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DR   EMBL; AE005174; AAG58652.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37814.1; -; Genomic_DNA.
DR   PIR; G91177; G91177.
DR   PIR; H86023; H86023.
DR   RefSeq; NP_312418.1; NC_002695.1.
DR   RefSeq; WP_000965672.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AET6; -.
DR   SMR; P0AET6; -.
DR   STRING; 155864.EDL933_4761; -.
DR   EnsemblBacteria; AAG58652; AAG58652; Z4923.
DR   EnsemblBacteria; BAB37814; BAB37814; ECs_4391.
DR   GeneID; 66672605; -.
DR   GeneID; 915752; -.
DR   KEGG; ece:Z4923; -.
DR   KEGG; ecs:ECs_4391; -.
DR   PATRIC; fig|386585.9.peg.4588; -.
DR   eggNOG; COG3247; Bacteria.
DR   HOGENOM; CLU_091585_6_0_6; -.
DR   OMA; VRGPQFG; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005325; DUF308_memb.
DR   Pfam; PF03729; DUF308; 2.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..190
FT                   /note="Protein HdeD"
FT                   /id="PRO_0000083936"
FT   TOPO_DOM        1..25
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        45..47
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..76
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        100..103
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        127..138
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        162..164
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        188..190
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   190 AA;  20903 MW;  59FEAD58A13F7ECE CRC64;
     MLYIDKATIL KFDLEMLKKH RRAIQFIAVL LFIVGLLCIS FPFVSGDILS TVVGALLICS
     GIALIVGLFS NRSHNFWPVL SGFLVAVAYL LIGYFFIRAP ELGIFAIAAF IAGLFCVAGV
     IRLMSWYRQR SMKGSWLQLV IGVLDIVIAW IFLGATPMVS VTLVSTLVGI ELIFSAASLF
     SFASLFVKQQ