HDED_ECOLI
ID HDED_ECOLI Reviewed; 190 AA.
AC P0AET5; P26603; P28326; Q2M7H3;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Protein HdeD;
GN Name=hdeD; Synonyms=yhiA; OrderedLocusNames=b3511, JW3479;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=8244952; DOI=10.1128/jb.175.23.7747-7748.1993;
RA Yoshida T., Ueguchi C., Mizuno T.;
RT "Physical map location of a set of Escherichia coli genes (hde) whose
RT expression is affected by the nucleoid protein H-NS.";
RL J. Bacteriol. 175:7747-7748(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-106.
RC STRAIN=K12;
RX PubMed=8455549; DOI=10.1007/bf00282791;
RA Yoshida T., Ueguchi C., Yamada H., Mizuno T.;
RT "Function of the Escherichia coli nucleoid protein, H-NS: molecular
RT analysis of a subset of proteins whose expression is enhanced in a hns
RT deletion mutant.";
RL Mol. Gen. Genet. 237:113-122(1993).
RN [6]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA01882.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D11389; BAA01985.1; -; Genomic_DNA.
DR EMBL; U00039; AAB18487.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76536.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77783.1; -; Genomic_DNA.
DR EMBL; D11109; BAA01882.1; ALT_INIT; Genomic_DNA.
DR PIR; S47731; S47731.
DR RefSeq; NP_417968.1; NC_000913.3.
DR RefSeq; WP_000965672.1; NZ_STEB01000046.1.
DR AlphaFoldDB; P0AET5; -.
DR SMR; P0AET5; -.
DR BioGRID; 4259561; 5.
DR DIP; DIP-48170N; -.
DR IntAct; P0AET5; 1.
DR STRING; 511145.b3511; -.
DR TCDB; 9.B.36.1.1; the acid resistance membrane protein (hded) family.
DR jPOST; P0AET5; -.
DR PaxDb; P0AET5; -.
DR PRIDE; P0AET5; -.
DR EnsemblBacteria; AAC76536; AAC76536; b3511.
DR EnsemblBacteria; BAE77783; BAE77783; BAE77783.
DR GeneID; 66672605; -.
DR GeneID; 948024; -.
DR KEGG; ecj:JW3479; -.
DR KEGG; eco:b3511; -.
DR PATRIC; fig|1411691.4.peg.3208; -.
DR EchoBASE; EB1458; -.
DR eggNOG; COG3247; Bacteria.
DR HOGENOM; CLU_091585_6_0_6; -.
DR InParanoid; P0AET5; -.
DR OMA; VRGPQFG; -.
DR PhylomeDB; P0AET5; -.
DR BioCyc; EcoCyc:EG11495-MON; -.
DR PRO; PR:P0AET5; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0009268; P:response to pH; IMP:EcoCyc.
DR InterPro; IPR005325; DUF308_memb.
DR Pfam; PF03729; DUF308; 2.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..190
FT /note="Protein HdeD"
FT /id="PRO_0000083935"
FT TOPO_DOM 1..25
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 45..47
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 71..76
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 100..103
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 127..138
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 162..164
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 188..190
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 190 AA; 20903 MW; 59FEAD58A13F7ECE CRC64;
MLYIDKATIL KFDLEMLKKH RRAIQFIAVL LFIVGLLCIS FPFVSGDILS TVVGALLICS
GIALIVGLFS NRSHNFWPVL SGFLVAVAYL LIGYFFIRAP ELGIFAIAAF IAGLFCVAGV
IRLMSWYRQR SMKGSWLQLV IGVLDIVIAW IFLGATPMVS VTLVSTLVGI ELIFSAASLF
SFASLFVKQQ
