HDG10_ARATH
ID HDG10_ARATH Reviewed; 708 AA.
AC Q9S9Z0; Q9LNM7;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Homeobox-leucine zipper protein HDG10 {ECO:0000303|PubMed:16778018};
DE AltName: Full=HD-ZIP protein HDG10 {ECO:0000303|PubMed:16778018};
DE AltName: Full=Homeodomain GLABRA 2-like protein 10 {ECO:0000303|PubMed:10809443};
DE AltName: Full=Homeodomain transcription factor HDG10 {ECO:0000303|PubMed:16778018};
DE AltName: Full=Protein HOMEODOMAIN GLABROUS 10 {ECO:0000303|PubMed:16778018};
GN Name=HDG10 {ECO:0000303|PubMed:16778018};
GN Synonyms=HDGL2-10 {ECO:0000303|PubMed:10809443};
GN OrderedLocusNames=At1g34650 {ECO:0000312|Araport:AT1G34650};
GN ORFNames=F12K21.1 {ECO:0000312|EMBL:AAF79277.1},
GN F21H2.11 {ECO:0000312|EMBL:AAD46012.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=10809443; DOI=10.1023/a:1006368316413;
RA Tavares R., Aubourg S., Lecharny A., Kreis M.;
RT "Organization and structural evolution of four multigene families in
RT Arabidopsis thaliana: AtLCAD, AtLGT, AtMYST and AtHD-GL2.";
RL Plant Mol. Biol. 42:703-717(2000).
RN [4]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16778018; DOI=10.1104/pp.106.077388;
RA Nakamura M., Katsumata H., Abe M., Yabe N., Komeda Y., Yamamoto K.T.,
RA Takahashi T.;
RT "Characterization of the class IV homeodomain-leucine zipper gene family in
RT Arabidopsis.";
RL Plant Physiol. 141:1363-1375(2006).
RN [5]
RP INTERACTION WITH ANT; BBM AND AIL1.
RC STRAIN=cv. Columbia;
RX PubMed=25564655; DOI=10.1242/dev.117168;
RA Horstman A., Fukuoka H., Muino J.M., Nitsch L., Guo C., Passarinho P.,
RA Sanchez-Perez G., Immink R., Angenent G., Boutilier K.;
RT "AIL and HDG proteins act antagonistically to control cell proliferation.";
RL Development 142:454-464(2015).
CC -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with ANT, BBM and AIL1.
CC {ECO:0000269|PubMed:25564655}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in exclusively in anthers with highest
CC levels in the tapetum and pollen grains. {ECO:0000269|PubMed:16778018}.
CC -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class IV subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79277.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007894; AAD46012.1; -; Genomic_DNA.
DR EMBL; AC023279; AAF79277.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31732.1; -; Genomic_DNA.
DR PIR; B86470; B86470.
DR RefSeq; NP_174724.1; NM_103188.3.
DR AlphaFoldDB; Q9S9Z0; -.
DR STRING; 3702.AT1G34650.1; -.
DR PaxDb; Q9S9Z0; -.
DR PRIDE; Q9S9Z0; -.
DR ProteomicsDB; 247353; -.
DR EnsemblPlants; AT1G34650.1; AT1G34650.1; AT1G34650.
DR GeneID; 840369; -.
DR Gramene; AT1G34650.1; AT1G34650.1; AT1G34650.
DR KEGG; ath:AT1G34650; -.
DR Araport; AT1G34650; -.
DR TAIR; locus:2023932; AT1G34650.
DR eggNOG; ENOG502QTNV; Eukaryota.
DR HOGENOM; CLU_015002_2_1_1; -.
DR InParanoid; Q9S9Z0; -.
DR OMA; MPEKSEF; -.
DR OrthoDB; 1580567at2759; -.
DR PhylomeDB; Q9S9Z0; -.
DR PRO; PR:Q9S9Z0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9S9Z0; baseline and differential.
DR Genevisible; Q9S9Z0; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR042160; GLABRA2/ANL2/PDF2/ATML1-like.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR45654; PTHR45654; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50848; START; 1.
PE 1: Evidence at protein level;
KW Coiled coil; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..708
FT /note="Homeobox-leucine zipper protein HDG10"
FT /id="PRO_0000331671"
FT DOMAIN 218..456
FT /note="START"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00197"
FT DNA_BIND 16..75
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 119..141
FT /evidence="ECO:0000255"
FT COMPBIAS 163..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 80058 MW; 544AC437BAD01E79 CRC64;
MDSSHNDSSS DEEGIDSNNR RHHSNHQVQR LEAFFHECPH PDDSQRRQLG NELNLKHKQI
KFWFQNRRTQ ARIHNEKADN IALRVENMKI RCVNEAMEKA LETVLCPPCG GPHGKEEQLC
NLQKLRTKNV ILKTEYERLS SYLTKHGGYS IPSVDALPDL HGPSTYGSTS NNRPASYGSS
SNHLPQQSSL LRRPFTRELI NTTPLPKPVL LQHFQQLSQL EKNRMFEIAK NAVAEVMSLI
QMEHSMWIKS TIDGRAIIDP GNYKRYFTKN SHLKSRSALQ SHHESSMEVV VVQMDARNLV
DMFLNTEKWA RLFPTIVTEA KTIHVLDSMD HPRQTFSRVV YEQLHILSPL VLPREFIILR
TCQQMKEDLW LIADVSCYLQ NVEFESTAPI CTKRPSGVLI QALPHGRSKV TWIEHVEVTD
KVWPHQLYRD LLYGGFGYGA RRWTATLQRM CERLSLYSMT DFPPTDYPGV VKTIEGRRSV
MSLGERMLKN FAWIMKMSDK LDLPQQSGAN NSGVRISVRT NTEAGQPPGL IVCAGSSLSL
PLPPLQVYDF LRNLEVRHQW DVHCQGNPVT EAARFVTGPD QKNNVTFLQP SSVGEYKLMI
LQDGFIDALG GMVVYAPMNL NTAYSAISGQ VDPSTIPILP SGFIISRDSH PSSSEVDGGS
MTLLTLAFQI FVTGPSYYTD LNLKDSATTV NTLVSSAVQR IKAMLNCE
