HDHD3_DANRE
ID HDHD3_DANRE Reviewed; 242 AA.
AC Q7T012; Q1JQ17; Q502F9;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 3;
GN Name=hdhd3; ORFNames=si:ch211-10e8.6, zgc:136363;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Liver, and Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL732598; CAE30381.1; -; Genomic_DNA.
DR EMBL; BC095713; AAH95713.1; -; mRNA.
DR EMBL; BC116519; AAI16520.1; -; mRNA.
DR RefSeq; NP_001038732.2; NM_001045267.2.
DR AlphaFoldDB; Q7T012; -.
DR SMR; Q7T012; -.
DR STRING; 7955.ENSDARP00000094552; -.
DR PaxDb; Q7T012; -.
DR PRIDE; Q7T012; -.
DR Ensembl; ENSDART00000103776; ENSDARP00000094552; ENSDARG00000053934.
DR GeneID; 553464; -.
DR KEGG; dre:553464; -.
DR CTD; 81932; -.
DR ZFIN; ZDB-GENE-040724-118; hdhd3.
DR eggNOG; KOG3085; Eukaryota.
DR GeneTree; ENSGT00390000015582; -.
DR HOGENOM; CLU_045011_8_0_1; -.
DR InParanoid; Q7T012; -.
DR OMA; WWRQLIA; -.
DR OrthoDB; 1119971at2759; -.
DR PhylomeDB; Q7T012; -.
DR TreeFam; TF315144; -.
DR PRO; PR:Q7T012; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 6.
DR Bgee; ENSDARG00000053934; Expressed in testis and 21 other tissues.
DR ExpressionAtlas; Q7T012; baseline.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR Gene3D; 1.10.150.720; -; 1.
DR Gene3D; 3.40.50.1000; -; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006439; HAD-SF_hydro_IA.
DR InterPro; IPR011949; HAD-SF_hydro_IA_REG-2-like.
DR InterPro; IPR044924; HAD-SF_hydro_IA_REG-2-like_cap.
DR InterPro; IPR023214; HAD_sf.
DR PRINTS; PR00413; HADHALOGNASE.
DR SUPFAM; SSF56784; SSF56784; 1.
DR TIGRFAMs; TIGR02252; DREG-2; 1.
DR TIGRFAMs; TIGR01549; HAD-SF-IA-v1; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..242
FT /note="Haloacid dehalogenase-like hydrolase domain-
FT containing protein 3"
FT /id="PRO_0000287315"
FT CONFLICT 49
FT /note="L -> Q (in Ref. 2; AAI16520)"
FT /evidence="ECO:0000305"
FT CONFLICT 155
FT /note="I -> L (in Ref. 2; AAI16520)"
FT /evidence="ECO:0000305"
FT CONFLICT 216
FT /note="Missing (in Ref. 2; AAI16520)"
FT /evidence="ECO:0000305"
FT CONFLICT 240
FT /note="N -> D (in Ref. 2; AAH95713/AAI16520)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 242 AA; 27204 MW; 00AC439645B4E53B CRC64;
MRVPVRWVLW DVKDTLLKVR RSVGEQYCRE AQQAGLQLSP AQVETAFRLA YKQKSQLLPN
YGRAQGMDSQ VWWTGLVRDT FGQCGVHDPA LLDKLANNLY HNFCGPENWE VFSDSNSTLK
SCTALGLKQG VVSNFDRRLE GILRGCGLLT HFSFIVTSED ARVAKPDPAI FSQALERCGV
PASSVVHVGD HYVKDYLTSR SLGIRGYLLN RKDGQKTHLD IPPEHILQSL DELPARLQHN
TD
