ID   HDLB_ARCPA              Reviewed;         299 AA.
AC   P84623; D2REQ5;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 2.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Heterodisulfide reductase subunit B-like protein;
DE            EC=1.8.-.-;
GN   Name=hdlB; OrderedLocusNames=Arcpr_1553;
OS   Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=572546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5631 / JCM 9629 / NBRC 100127 / Av18;
RX   PubMed=21304717; DOI=10.4056/sigs.942153;
RA   von Jan M., Lapidus A., Del Rio T.G., Copeland A., Tice H., Cheng J.F.,
RA   Lucas S., Chen F., Nolan M., Goodwin L., Han C., Pitluck S., Liolios K.,
RA   Ivanova N., Mavromatis K., Ovchinnikova G., Chertkov O., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Saunders E.,
RA   Brettin T., Detter J.C., Chain P., Eichinger K., Huber H., Spring S.,
RA   Rohde M., Goker M., Wirth R., Woyke T., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Archaeoglobus profundus type strain (AV18).";
RL   Stand. Genomic Sci. 2:327-346(2010).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 2-21, FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
RX   PubMed=15009189; DOI=10.1111/j.1432-1033.2004.04013.x;
RA   Mander G.J., Pierik A.J., Huber H., Hedderich R.;
RT   "Two distinct heterodisulfide reductase-like enzymes in the sulfate-
RT   reducing archaeon Archaeoglobus profundus.";
RL   Eur. J. Biochem. 271:1106-1116(2004).
CC   -!- FUNCTION: Has oxidoreductase activity. The Hdl and Mvh subunits may
CC       together mediate electron transfer from hydrogen to an unidentified
CC       electron acceptor on the cytoplasmic side of the membrane.
CC       {ECO:0000269|PubMed:15009189}.
CC   -!- SUBUNIT: The heterodisulfide reductase is composed of three subunits;
CC       HdlA, HdlB and HdlC. It forms a complex with the F420-non-reducing
CC       hydrogenase (Mvh), which provides the reducing equivalents to the
CC       heterodisulfide reductase. {ECO:0000269|PubMed:15009189}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15009189}.
CC   -!- SIMILARITY: Belongs to the HdrB family. {ECO:0000305}.
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DR   EMBL; CP001857; ADB58599.1; -; Genomic_DNA.
DR   RefSeq; WP_012940935.1; NC_013741.1.
DR   AlphaFoldDB; P84623; -.
DR   SMR; P84623; -.
DR   STRING; 572546.Arcpr_1553; -.
DR   PRIDE; P84623; -.
DR   EnsemblBacteria; ADB58599; ADB58599; Arcpr_1553.
DR   GeneID; 8740243; -.
DR   KEGG; apo:Arcpr_1553; -.
DR   eggNOG; arCOG00338; Archaea.
DR   HOGENOM; CLU_052147_1_0_2; -.
DR   OMA; PGCVAQG; -.
DR   OrthoDB; 73750at2157; -.
DR   Proteomes; UP000001901; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   Pfam; PF02754; CCG; 2.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Oxidoreductase; Reference proteome.
FT   CHAIN           1..299
FT                   /note="Heterodisulfide reductase subunit B-like protein"
FT                   /id="PRO_0000150071"
FT   CONFLICT        2
FT                   /note="V -> G (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   299 AA;  33460 MW;  469EAAA28B96A4DC CRC64;
     MVKYGLFLGC NISFNRPDVE VSMRSIFPAL GIELDDLVGQ SCCPTWGTMP SVDIVGWCAV
     AARNLALGEE KGIDLMTACN SCYGSLNEAR HKMLTNPEIH RKVNEILATI GKRYEGKAKC
     RHVAWVLYKD VGLEKLKESI KYTLDGITVA VQPGCHFLWP SEVYPDKEED PFNPKVLREL
     CEALGAEAPY YTKLIECCGM GALRSTDPEK SFKLVKEKME NIKEEIDADL IVTTCSSCLI
     QLDDAQERLR KEGKINFSIP VLHLVQVIAL CMGFDPEKVA GICVTPRDEI IKRILENKR