ID   HDRB1_METJA             Reviewed;         294 AA.
AC   Q58153;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=CoB--CoM heterodisulfide reductase subunit B 1 {ECO:0000305};
DE            EC=1.8.98.- {ECO:0000305};
GN   Name=hdrB1; OrderedLocusNames=MJ0743;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible reduction of
CC       CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB
CC       (coenzyme B). {ECO:0000250|UniProtKB:Q6LY38}.
CC   -!- PATHWAY: Cofactor metabolism; coenzyme M-coenzyme B heterodisulfide
CC       reduction; coenzyme B and coenzyme M from coenzyme M-coenzyme B
CC       heterodisulfide: step 1/1. {ECO:0000250|UniProtKB:Q6LY38}.
CC   -!- SUBUNIT: The heterodisulfide reductase is composed of three subunits;
CC       HdrA, HdrB and HdrC. {ECO:0000250|UniProtKB:Q6LY38}.
CC   -!- SIMILARITY: Belongs to the HdrB family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98737.1; -; Genomic_DNA.
DR   PIR; G64392; G64392.
DR   RefSeq; WP_010870248.1; NC_000909.1.
DR   AlphaFoldDB; Q58153; -.
DR   SMR; Q58153; -.
DR   STRING; 243232.MJ_0743; -.
DR   PRIDE; Q58153; -.
DR   EnsemblBacteria; AAB98737; AAB98737; MJ_0743.
DR   GeneID; 1451620; -.
DR   KEGG; mja:MJ_0743; -.
DR   eggNOG; arCOG00338; Archaea.
DR   HOGENOM; CLU_052147_1_0_2; -.
DR   InParanoid; Q58153; -.
DR   OMA; SCCGASH; -.
DR   OrthoDB; 73750at2157; -.
DR   PhylomeDB; Q58153; -.
DR   UniPathway; UPA00647; UER00700.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051912; F:CoB--CoM heterodisulfide reductase activity; IEA:InterPro.
DR   GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR017678; CoB/CoM_hetero-S_Rdtase_bsu.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   Pfam; PF02754; CCG; 2.
DR   TIGRFAMs; TIGR03288; CoB_CoM_SS_B; 1.
PE   3: Inferred from homology;
KW   Methanogenesis; Oxidoreductase; Reference proteome.
FT   CHAIN           1..294
FT                   /note="CoB--CoM heterodisulfide reductase subunit B 1"
FT                   /id="PRO_0000150065"
SQ   SEQUENCE   294 AA;  33310 MW;  C8D5DDCE6FDC8560 CRC64;
     MEFVFFLGCI APNRYPGIEK ATYITMEKLG IKLHPFEKAS CCPAPGVFGS FDLKTWLTLA
     ARNLCMAEEV EMDILTICNG CYGSLYEANH LLKENEKARK MVNEILSKYG LEYKGKVRVR
     HLPEVLYYDL GVDRIKEEIT NPLNVNVAVH YGCHYLKPTD IKKLESSERP RSFDELVEAL
     GAVSVNYKDK NMCCGAGGGV RARNLDVALK MTKTKLENIK EAKADCITEV CPFCHLQFDR
     GQVEIKEKFG EEYNIPVIHY SQLLGLAMGM SPKDVALDLH FIPTDEFIKK IDRH