HEAT1_ARATH
ID HEAT1_ARATH Reviewed; 2197 AA.
AC Q9C8Z4; F4JAY2; Q56X73;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2011, sequence version 3.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=Uncharacterized protein At3g06530;
GN OrderedLocusNames=At3g06530; ORFNames=F5E6.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1898-2197.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9C8Z4-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51331.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC020580; AAG51331.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74407.1; -; Genomic_DNA.
DR EMBL; AK221804; BAD93973.1; -; mRNA.
DR RefSeq; NP_187305.5; NM_111529.6. [Q9C8Z4-1]
DR AlphaFoldDB; Q9C8Z4; -.
DR SMR; Q9C8Z4; -.
DR BioGRID; 5166; 12.
DR IntAct; Q9C8Z4; 1.
DR STRING; 3702.AT3G06530.2; -.
DR iPTMnet; Q9C8Z4; -.
DR PaxDb; Q9C8Z4; -.
DR PRIDE; Q9C8Z4; -.
DR ProteomicsDB; 247355; -. [Q9C8Z4-1]
DR EnsemblPlants; AT3G06530.1; AT3G06530.1; AT3G06530. [Q9C8Z4-1]
DR GeneID; 819831; -.
DR Gramene; AT3G06530.1; AT3G06530.1; AT3G06530. [Q9C8Z4-1]
DR KEGG; ath:AT3G06530; -.
DR Araport; AT3G06530; -.
DR eggNOG; KOG1837; Eukaryota.
DR HOGENOM; CLU_001128_3_0_1; -.
DR InParanoid; Q9C8Z4; -.
DR PRO; PR:Q9C8Z4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9C8Z4; baseline and differential.
DR Genevisible; Q9C8Z4; AT.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0034455; C:t-UTP complex; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; PTHR13457; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; SSF48371; 3.
PE 1: Evidence at protein level;
KW Acetylation; Alternative splicing; Nucleus; Reference proteome;
KW Ribonucleoprotein; Ribosome biogenesis; rRNA processing.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..2197
FT /note="Uncharacterized protein At3g06530"
FT /id="PRO_0000186205"
FT REPEAT 2159..2195
FT /note="HEAT"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 2197 AA; 246322 MW; E7BFBEFAB126A382 CRC64;
MSSSIVSQLQ ALKSVLQADT EPSKRPFTRP SILFSPKEAA DFDIESIYEL GLKGLEVLGN
KDERFKNYMN DLFSHKSKEI DRELLGKEEN ARIDSSISSY LRLLSGYLQF RASLETLEYL
IRRYKIHIYN LEDVVLCALP YHDTHAFVRI VQLLSTGNSK WKFLDGVKNS GAPPPRSVIV
QQCIRDKQVL EALCDYASRT KKYQPSKPVV SFSTAVVVGV LGSVPTVDGD IVKTILPFVD
SGLQSGVKGC LDQQAGALMV VGMLANRAVL NTNLIKRLMR SIIDIGREHA KESSDPHSLR
LSLMALINFV QLQSVDLIPR KALDLFNEIR DISGVLLGLS KEFNIKRFLA VLLDSLLFYS
SSDDKCCEVL ASIIETVPVS NLVDHLISKV FSLCMTQYQK NSDFRSSTSG SWAKKFLVVV
SKKYPAELRA AVPKFLEATE VQSKKEDLKL EMLSCMLDGN SDMSHPFVDS KLWFRLHHPR
AAVRCAALSS LNGVLKDDSS KAENLVTIQD AILRQLWDDD LAVVQAALSF DKLPNIITSS
GLLDALLHVV KRCVGILVSG VSHNVQLAVD VVALSLKIAV SSFGNQTDST EKVTSAMFPF
LLIQPKTWNL NLLVLKLGKD VNWPLFKNLA ADDGMKKLPD IMSTNLSSIS MDIINDLGEA
LSLDPDERRI ELIERACNYK LSEVLETCSN IKCSEQDRNK LQKGLLIRES VSALNIDVIN
KLVEAFMMHP ADYIQWLTVS CRDSTLSKTL FYMILMHSLQ KMNSSSDPSQ LLDLFELCFP
VLKTEWEELE VEVDVSLKEL SKSNCQELLY QLLDTSDFTA LNSKVLICLF WKLGESFIKL
EPAHDASVLN KRLSSGLEDL FFFFATTRLR HVFKEHLHFR VREAKVCPVL FLSRLISRED
VPPLVQIESL RCFSYLCSSG NNEWLIQVFS SFPVLLVPMS SDNQDVKAAA INCIEALFNL
RAAIYGSSFD ELLGMIVQQR RLILSDNKFF ASYLTSLLSS TTNDLLVPVG LQKRFDQSTK
ENILSVILLC AEDLPAYGKL RVLSLLKDLG IMLMRDEIVK LLSQLLDKRS QYYYKLDKTS
QPLSDTEVDL LCLLLECSMM RTSSFKGQSL DDHILSALNV DCMASERPAV ISPCLTILEK
LSNRFYDELQ TDVQIRFFHK LVSMFRSSNG SIQNGAKEAV LRLKLSSSTV VLALDRITQQ
DTLVIGSLSK KKKQKKNSKS CPEEDINSEE FRSGEKALSF IASLLDMLLL KKDLTHRESL
IRPLFKLLQR SMSKEWVKIA FSIEETSLQP PQDVRETTPT FISSIQQTLL LILKDIFDSL
NMNPLKAEVA NEINVKMLVE LAHSSNDGVT RNHIFSLFTA IVKFVPDKVL DHIISILTLV
GESTVTQIDS HSKSIFEGFI SMVIPFWLSK TKSEEQLLQI FVKVLPDIVE HRRRSIVAYL
LGVIGERNGL PALLVLLFKS LISRKDSAWL GNANVSESFA SIVKKEWEYS FAMEICEQYS
SSTWLSSLVI LLQTISKDSK QCFLQMRLVL EFVFQKLQDP EFAFAVSLEP RNNVSVGIQQ
ELQELMKCCI CLLQAIDAKK EKDVTSSVRN EIRMRIHDVL MTVTGAMDLS IYFRVVTSLL
QQQTDYNGTK KVLGLISERA KDTSSSKMKH KRKISNQKGR NSWLNLDEVA VDSFGKMCEE
IVHLINATDD ESGVPVKRAA ISTLEVLAGR FPSGHPIFRK CLAAVAECIS SKNLGVSSSC
LRTTGALINV LGPKALIELP CIMKNLVKQS LEVSFASQSG RNATAEEQLL MLSVLVTLEA
VIDKLGGFLN PHLGDIMKIM VLHPEYVSDF DKNLKSKANA IRRLLTDKIP VRLTLQPLLR
IYNEAVSSGN ASLVIAFNML EDLVVKMDRS SIVSSHGKIF DQCLVALDIR RLNPAAIQNI
DDAERSVTSA MVALTKKLTE SEFRPLFIRS IDWAESDVVD GSGSENKSID RAISFYGLVD
RLCESHRSIF VPYFKYVLDG IVAHLTTAEA SVSTRKKKKA KIQQTSDSIQ PKSWHLRALV
LSCLKNCFLH DTGSLKFLDT NNFQVLLKPI VSQLVVEPPS SLKEHPHVPS VDEVDDLLVS
CIGQMAVASG SDLLWKPLNH EVLMQTRSES VRSRMLSLRS VKQMLDNLKE EYLVLLAETI
PFLAELLEDV ELSVKSLAQD IIKQMEEMSG ESLAEYL
