ID   HELI1_HVAVE             Reviewed;         944 AA.
AC   A4KX71;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=Putative ATP-dependent RNA helicase;
DE            EC=3.6.4.13;
GN   ORFNames=ORF15;
OS   Heliothis virescens ascovirus 3e (HvAV-3e).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Ascoviridae; Ascovirus.
OX   NCBI_TaxID=260797;
OH   NCBI_TaxID=7100; Noctuidae (owlet moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17374755; DOI=10.1099/vir.0.82651-0;
RA   Asgari S., Davis J., Wood D., Wilson P., McGrath A.;
RT   "Sequence and organization of the Heliothis virescens ascovirus genome.";
RL   J. Gen. Virol. 88:1120-1132(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; EF133465; ABO37201.1; -; Genomic_DNA.
DR   RefSeq; YP_001110868.1; NC_009233.1.
DR   PRIDE; A4KX71; -.
DR   GeneID; 5076031; -.
DR   KEGG; vg:5076031; -.
DR   Proteomes; UP000001324; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..944
FT                   /note="Putative ATP-dependent RNA helicase"
FT                   /id="PRO_0000329954"
FT   DOMAIN          66..235
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          451..523
FT                   /note="Helicase C-terminal"
FT   MOTIF           183..186
FT                   /note="DEAH box"
FT   BINDING         79..86
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   944 AA;  106260 MW;  07C1405F95CA2860 CRC64;
     MLKYALPLYP IAESTDESWS YEHLDKLTTY AEFNETQLLY SEDDDRDHNN ETRKPMPHQI
     LVANYTTPRS PIDGIIVIHG VGTGKTLTAI LAMINNITAG HDQGMKRGLV LTPNRAVMNS
     FRNELNCYYR SRFSDRHLND FEIDRYLSKT FFFNTITAFA NTVSRTSDVV LHKEWNATFV
     VIDEAHDLSV QGVDYPKING FLKLLTSRKV ILLTATPMRN NLSDLVPLHN LLMKLSTHDI
     TVEQFNRDLV TRENCAEYVC ARESPTEYFL RKFAGLVSYL PSIVDVNEVD IVNVGERGLY
     GLRNTVIVVH DMSDVMSATY HYAGAGERSD RDVALLRQRQ ICRFVFPDGT YGAEGYATWM
     DNKTGRPTRK FLDMLRGGTG TSREDILKNV AKYSPRYAWI AKSVIDAAER GEKSMVYDDL
     VTGSGLLVFA AVLEALGLER GYGRGARSFL CLTREVMTVP SIVSALKIFN DRKNVKGANV
     AIILGSRVIA EGITLKDVIH EHVVAHWNDA ETEQIIGRGI RYQSHAYTIA DWGSDAKPNV
     FVYRHATIDS RKKNIKTVDI LMYATSEAKR KNIDGALRAL SSVALTCRNS NNTFVKSVYR
     GRYTGRNITN DNTIPLDAPR VTKSFIAQLD QLFDYRNQNV VVKVDSLLKM FNIDPNSKYS
     LELLFVIMNT IQKHGQLDVD KYIDCNGQYI SISKCVDEFR QRPTFVYPFV LDNVSLYGLD
     VYRDTLAKDI ISPLILLDAE RHTGGLYPMT RLPVIVIQGL LELAISTQGT KDPYDTLNKM
     IQYYGTSTNG DNDIRAAVWL ATTTGDDSGY RILNEHSGSW VSCPSSMVPF VQAMKSSVEA
     QLNNDMLAKN LKYYGVLHPS TDDFCIKTVS QNTPTNRRCV MTGRKCVTWS GEKLKELARD
     IGIDTGDSSS VQNRKTICYN IRSKLEELGA VITDVTCGVQ AKRK