ID   HELI1_SFAVA             Reviewed;         978 AA.
AC   Q0E592;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Putative ATP-dependent RNA helicase;
DE            EC=3.6.4.13;
GN   ORFNames=ORF9;
OS   Spodoptera frugiperda ascovirus 1a (SfAV-1a).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Ascoviridae; Ascovirus.
OX   NCBI_TaxID=113370;
OH   NCBI_TaxID=7108; Spodoptera frugiperda (Fall armyworm).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16987980; DOI=10.1128/jvi.01639-06;
RA   Bideshi D.K., Demattei M.V., Rouleux-Bonnin F., Stasiak K., Tan Y.,
RA   Bigot S., Bigot Y., Federici B.A.;
RT   "Genomic sequence of Spodoptera frugiperda Ascovirus 1a, an enveloped,
RT   double-stranded DNA insect virus that manipulates apoptosis for viral
RT   reproduction.";
RL   J. Virol. 80:11791-11805(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC       {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-29 is the initiator.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM398843; CAL44609.1; -; Genomic_DNA.
DR   RefSeq; YP_762364.1; NC_008361.1.
DR   PRIDE; Q0E592; -.
DR   GeneID; 4306176; -.
DR   KEGG; vg:4306176; -.
DR   Proteomes; UP000008030; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..978
FT                   /note="Putative ATP-dependent RNA helicase"
FT                   /id="PRO_0000329955"
FT   DOMAIN          94..261
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   MOTIF           209..212
FT                   /note="DEAH box"
FT   BINDING         107..114
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   978 AA;  110798 MW;  D9C8CFE25FF8157A CRC64;
     MKFNFCLVFF PCPCYFSTVV YYVNEQCTML KYALPLYPVV DAIDESWSYE HLDKLTKYNE
     FTDTQLLYSN DDVRDFNNTS RVPMPHQVLV ANYTTPKSPV EGVLVVHGVG TGKTMTAILA
     MLNNINVPGG LKRGLVLTPN RAVLSAFRDE LHAYYKSRFS DRHVNEFEME KYLSETFAFN
     TITSFANTID RTADVVLHKE WNATFVVIDE AHDLTMQGVD YPKINGFLKL LTSRKILLLT
     ATPMRNNISD LVPLHNLLMR NRTHDITVEQ FNRDMVVRIN DVNDVYTVEK PNEYFRRKFA
     GLVSYLPSNG RDALDVNIVQ VGRTGVYGLK YTHVVEHDMS DDMAMVYRTV DDATRNDRDV
     ALLRQRQVSR FVFPDGTYGT TGYQSWMDSK TGRPKRKLLD ALRGGASDRA AILDNVAKYS
     PRYAWIARNV IEAAERGEKS MVYDDLVTGS GLLVFAAVLE ALGLERGTGK GAGSFLCLTR
     EVMTVNAIVS AIKNIQQRQQ LRRFRGRYRV RFASHRRSIT LKDVIHEHVV AHRNDAETEQ
     IIGRGIRYKS HANTIANWKS STRPNVFIYR HATVDSRSPN TRTVDILMLA TSERKRLNIN
     SAISALSSVA LTCNGCNPSS QTPPVPPAYR GYYKGVDVSD DNTIPLDPPR ITNSFIVKLD
     EEFDFRRQNV TVKVDSLLKL FNLDPSSVEA LKMLFVIMNT IQTHGQLDVD KYIDCNGQYV
     TISKCVDEFR QRPTFVYPYL VRNTSVYGVG VYRDALAESV ITPNMMRDIE RSVTTFPYPI
     DKLPVMVLQG LLETAIVTKG VRDPYNTLGD MVQYYAYGDN DPDVEAAVWL ALAAGEGQDY
     RILTTVGEDG VRRDRYWINC PNRYVDRVVR MKSEREAQIN DMVRSKRLKY YGTKNPTTGD
     FCIRTVPDGS PTNRRCVLTG RKCVTWTSSK LREIGSGVGV RVAANSPRKA TCSAIEQEFG
     RLDALFAYVS CGVQAKRK