ANG1_EMENI
ID ANG1_EMENI Reviewed; 277 AA.
AC Q00746; C8VPP3; Q5BC98;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Antigen 1;
DE AltName: Full=ASPND1;
DE Flags: Precursor;
GN Name=aspnd1; ORFNames=AN1832;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=G1059;
RX PubMed=9119471; DOI=10.1128/iai.65.4.1335-1344.1997;
RA Calera J.A., Ovejero M.C., Lopez-Medrano R., Segurado M., Puente P.,
RA Leal F.;
RT "Characterization of the Aspergillus nidulans aspnd1 gene demonstrates that
RT the ASPND1 antigen, which it encodes, and several A.fumigatus
RT immunodominant antigens belong to the same family.";
RL Infect. Immun. 65:1335-1344(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- SIMILARITY: Belongs to the ZPS1 family. {ECO:0000305}.
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DR EMBL; Z50175; CAA90537.1; -; Genomic_DNA.
DR EMBL; AACD01000029; EAA64997.1; -; Genomic_DNA.
DR EMBL; BN001307; CBF85648.1; -; Genomic_DNA.
DR RefSeq; XP_659436.1; XM_654344.1.
DR AlphaFoldDB; Q00746; -.
DR STRING; 162425.CADANIAP00008481; -.
DR EnsemblFungi; CBF85648; CBF85648; ANIA_01832.
DR EnsemblFungi; EAA64997; EAA64997; AN1832.2.
DR GeneID; 2874903; -.
DR KEGG; ani:AN1832.2; -.
DR VEuPathDB; FungiDB:AN1832; -.
DR eggNOG; ENOG502RTN8; Eukaryota.
DR HOGENOM; CLU_048223_0_0_1; -.
DR InParanoid; Q00746; -.
DR OMA; FPIHSSC; -.
DR OrthoDB; 1207536at2759; -.
DR Proteomes; UP000000560; Chromosome VII.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0009277; C:fungal-type cell wall; IBA:GO_Central.
DR GO; GO:0005178; F:integrin binding; IBA:GO_Central.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR CDD; cd11307; M35_Asp_f2_like; 1.
DR Gene3D; 3.40.390.10; -; 1.
DR InterPro; IPR029482; HRXXH.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR039124; PRA1-like.
DR PANTHER; PTHR39399; PTHR39399; 1.
DR Pfam; PF13933; HRXXH; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Reference proteome; Signal.
FT SIGNAL 1..16
FT /evidence="ECO:0000255"
FT CHAIN 17..277
FT /note="Antigen 1"
FT /id="PRO_0000041749"
FT REGION 230..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..259
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..277
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 41
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 71
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 127
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 200
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 277 AA; 30595 MW; 187F7361BB159790 CRC64;
MQLLALTLAL CASIAALPTQ QTPLPLEDPI KSPFPIHHSC NATEQRQLAT ALQETVTLAE
HAKDHILRWG NESAIYRKYF GDRPSLTAIG AYDIIVNGNP DNILFRCDNP DGNCALEGWG
GHWRGENASD ETVICELSYT TRRSLSTMCS QGYTISEWET NTFWAGDLLH RLYHMPAIGQ
GLVEHYADGY EGVLELAEGN RTEAVHDSET LQYFALEVYA YDVAVPGIGC VGGEEENDGQ
GEEQTEEPAQ DDQQDEAAEE EIPENCHTHE GGELHCT
