ID   HELS_CALMQ              Reviewed;         756 AA.
AC   A8MB76;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=ATP-dependent DNA helicase Hel308 {ECO:0000255|HAMAP-Rule:MF_00442};
DE            EC=3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_00442};
GN   Name=hel308 {ECO:0000255|HAMAP-Rule:MF_00442}; OrderedLocusNames=Cmaq_0318;
OS   Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 /
OS   IC-167).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Caldivirga.
OX   NCBI_TaxID=397948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700844 / DSM 13496 / JCM 10307 / IC-167;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C.,
RA   Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Biddle J.F., Zhang Z., Fitz-Gibbon S.T., Lowe T.M.,
RA   Saltikov C., House C.H., Richardson P.;
RT   "Complete sequence of Caldivirga maquilingensis IC-167.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-dependent ATPase and 3'-5' DNA helicase that may be
CC       involved in repair of stalled replication forks. {ECO:0000255|HAMAP-
CC       Rule:MF_00442}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00442};
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00442}.
CC   -!- SIMILARITY: Belongs to the helicase family. Hel308 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00442}.
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DR   EMBL; CP000852; ABW01166.1; -; Genomic_DNA.
DR   RefSeq; WP_012185386.1; NC_009954.1.
DR   AlphaFoldDB; A8MB76; -.
DR   SMR; A8MB76; -.
DR   STRING; 397948.Cmaq_0318; -.
DR   EnsemblBacteria; ABW01166; ABW01166; Cmaq_0318.
DR   GeneID; 5710426; -.
DR   KEGG; cma:Cmaq_0318; -.
DR   eggNOG; arCOG00553; Archaea.
DR   HOGENOM; CLU_006553_3_0_2; -.
DR   OMA; MFLNANI; -.
DR   OrthoDB; 9752at2157; -.
DR   Proteomes; UP000001137; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; -; 2.
DR   HAMAP; MF_00442; Helicase_Hel308; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR022965; Helicase_Hel308.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA damage; DNA repair; DNA-binding; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..756
FT                   /note="ATP-dependent DNA helicase Hel308"
FT                   /id="PRO_1000124579"
FT   DOMAIN          34..201
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00442"
FT   DOMAIN          233..435
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00442"
FT   MOTIF           146..149
FT                   /note="DEAH box"
FT   BINDING         29
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00442"
FT   BINDING         47..54
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00442"
SQ   SEQUENCE   756 AA;  84006 MW;  F99D4D6B75D0206E CRC64;
     MNIEELPLPS LLRDFLISKR GIRTLYPPQE EAIRAGLLNG ENILMVSATA SGKTLLAEVA
     AVNNVLVNDK KSLVAVPLKA LAFEKLNDFN TYSELGIRVA ASTGDYNSED KWLGSYDVII
     TTYEKLDSLL RLKPSWIWNV GQLIIDEIHF INDDERGPII ESIVAKLRML NLNPQIIGLS
     ATIGNPEELA NWLNAKLVKS DWRPVSLREG VYHKGVVTYV NDGEKRISGQ GDSLINLTVD
     TLNDGGQVLV FSSSRQGAVR IARKLAEYIC SSPVRYIDPG EAGKLAEEVR ETSSSRILAE
     ELTGLIKCGV SFHHAGLELE VRRVIEEGFR RGVLRVLAST TTLAAGVNLP ARRVIVNEYR
     RYEPGYGFIE IPVMEYKQMA GRAGRPGLDP YGEAIIIVSS KDEVDYVIDK YIKSPPEYVK
     SNFMNPTSLK FHTLSAVASQ YAETIDELVK FTSNTFAGFQ GKLSAMIQAN SVRRMISRII
     DELVDYGFII RNGDKLEATE VGAVVNRMYL DPDTAHVFIM GLRNLNSDAD LNAYSLMLVV
     KSPKIPKVKV RRNELDELAQ QAASMWSSIP LKPSDVDELV NYPEDYEDFL SEFKTAMALL
     EWINESNEDQ IMKTYDVQPG DLRVLSDQAE WLIGALQELA RTLGLSGNVV NGLRALRYRV
     KYGVNDELLE LVVNLEGVGR VRARALYAAG YRSIEDLAKA NVSDLTRIRG IGDKIAGSII
     EQAHQLVKDG RVIKFNESTV KGKTRRGGGG LLDHMY