ID   HELX_SACS2              Reviewed;         875 AA.
AC   P95949;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Uncharacterized ATP-dependent helicase SSO0112;
DE            EC=3.6.4.-;
GN   OrderedLocusNames=SSO0112; ORFNames=C04_010;
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=8899719; DOI=10.1111/j.1365-2958.1996.tb02666.x;
RA   Sensen C.W., Klenk H.-P., Singh R.K., Allard G., Chan C.C.-Y., Liu Q.Y.,
RA   Penny S.L., Young F., Schenk M.E., Gaasterland T., Doolittle W.F.,
RA   Ragan M.A., Charlebois R.L.;
RT   "Organizational characteristics and information content of an archaeal
RT   genome: 156 kb of sequence from Sulfolobus solfataricus P2.";
RL   Mol. Microbiol. 22:175-191(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
CC   -!- SIMILARITY: Belongs to the helicase family. {ECO:0000305}.
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DR   EMBL; Y08257; CAA69580.1; -; Genomic_DNA.
DR   EMBL; AE006641; AAK40467.1; -; Genomic_DNA.
DR   PIR; S75377; S75377.
DR   RefSeq; WP_009988933.1; NC_002754.1.
DR   AlphaFoldDB; P95949; -.
DR   SMR; P95949; -.
DR   STRING; 273057.SSO0112; -.
DR   PRIDE; P95949; -.
DR   EnsemblBacteria; AAK40467; AAK40467; SSO0112.
DR   GeneID; 44129071; -.
DR   KEGG; sso:SSO0112; -.
DR   PATRIC; fig|273057.12.peg.107; -.
DR   eggNOG; arCOG00557; Archaea.
DR   HOGENOM; CLU_002025_0_0_2; -.
DR   InParanoid; P95949; -.
DR   OMA; VVDEWHE; -.
DR   PhylomeDB; P95949; -.
DR   BRENDA; 3.6.4.12; 6163.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR017170; Lhr-like_ATP-dep_RNA_helic_prd.
DR   InterPro; IPR045628; Lhr_WH_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF19306; Lhr_WH; 1.
DR   PIRSF; PIRSF037307; Lhr-like_helic_prd; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..875
FT                   /note="Uncharacterized ATP-dependent helicase SSO0112"
FT                   /id="PRO_0000102198"
FT   DOMAIN          39..230
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          247..419
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   MOTIF           173..176
FT                   /note="DEIH box"
FT   BINDING         52..59
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   875 AA;  100393 MW;  920C7CF77BF8EC98 CRC64;
     MSNTYFYSDE EIYNLLRPYV AKWFRQKYTT FTPPQRAAIP LIKQNYNVLV SSPTGSGKTL
     AAFLGILDSL FELGDNNELE DKVYAIYISP LRALNNDMQR NLLEPLNELR QVNSKLPDVR
     VGIRTSDTTP YEKQKMLKKP PHILITTPES FGISITSPKF SQKLTDVKWI IVDEIHELAN
     SKRGAYLSAM LELFRNLITK KEFVRIGLSA TVSPLEEVAQ FLVGKDREYR IVDARFVKPV
     DIKVISPVKD LVHSSESEVD KGIYKTILNE VKKHRTTLIF TNTRHATERV AYKLRKLAEN
     EKVFDVDAIE AHHSSLSRDV RLDVEEKLKK GILKVVVSST SLELGIDIGY IDLVILLSSP
     KSVSRLLQRI GRAGHHIRSI SKGRVIVVDR DDLVECSVLA KLARDRKIDS IHIPKNPLDV
     LSQIIVSASL ISPIDRDDLF KILRRSYNFS DLSESDYSLV LRYLSGDFFG VELKNVYAKI
     RIKEEKIIYP KKGSRLIFYT NSGTIPDEAM ISVVTENNRY VGNLEEEFVE ILSPGDIFVL
     SGRTYEFIGS KGSKVIVKEA MGQRPTVPSW FSEMLPLAYE SALEIGKFRR EIAEMIKKGV
     THNEIIESIS KEYEIDKHAS MSIYTYILEQ YLFTNGKVPS DNLILIEIYD DEEGIRNYIF
     HALYGRRALD ALSRAFAYVV SEELDTDVRV SVTDNGFALS VKRDVPFDYN IKSLFEKITP
     DNVYDIVTRA VMRTEMLKRR FRHCAERSFM ILRRYKGRET NLERRELNSE ILLKAIREIG
     NFPVMKETIR EILEDHMDIL RAKEILKKIA SQEIKVDVFG PTNIPSPFSH SIILKGHSDV
     VLAEDRRELL KKLHERVVEF LRQKGVNIEL EYTSV