ID   ANGE2_BOVIN             Reviewed;         544 AA.
AC   A6H7I3;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Protein angel homolog 2;
GN   Name=ANGEL2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CCR4/nocturin family. {ECO:0000305}.
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DR   EMBL; BC146257; AAI46258.1; -; mRNA.
DR   RefSeq; NP_001092580.1; NM_001099110.1.
DR   AlphaFoldDB; A6H7I3; -.
DR   SMR; A6H7I3; -.
DR   STRING; 9913.ENSBTAP00000004825; -.
DR   PaxDb; A6H7I3; -.
DR   Ensembl; ENSBTAT00000004825; ENSBTAP00000004825; ENSBTAG00000003702.
DR   GeneID; 540507; -.
DR   KEGG; bta:540507; -.
DR   CTD; 90806; -.
DR   VEuPathDB; HostDB:ENSBTAG00000003702; -.
DR   VGNC; VGNC:25887; ANGEL2.
DR   eggNOG; KOG0620; Eukaryota.
DR   eggNOG; KOG2338; Eukaryota.
DR   GeneTree; ENSGT00940000157391; -.
DR   HOGENOM; CLU_016428_0_2_1; -.
DR   InParanoid; A6H7I3; -.
DR   OMA; WEYFCQQ; -.
DR   OrthoDB; 724242at2759; -.
DR   TreeFam; TF316126; -.
DR   Proteomes; UP000009136; Chromosome 16.
DR   Bgee; ENSBTAG00000003702; Expressed in oocyte and 111 other tissues.
DR   ExpressionAtlas; A6H7I3; baseline.
DR   GO; GO:0015030; C:Cajal body; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IBA:GO_Central.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IBA:GO_Central.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR   Gene3D; 3.60.10.10; -; 1.
DR   InterPro; IPR045816; ANGEL2_N.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   Pfam; PF19339; DUF5922; 2.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   SUPFAM; SSF56219; SSF56219; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..544
FT                   /note="Protein angel homolog 2"
FT                   /id="PRO_0000305079"
SQ   SEQUENCE   544 AA;  62348 MW;  44D041B4BE97A13C CRC64;
     MEAWRCVRRG YGRCVVGRGR YPMLPHHQKS LGRDWTTPWE NLQKCCWNRH ISSCMRWPGH
     YSRAPYPYFS SRHFSLNWRP PGLFESRAPF QYWNWRPDSL SQTSLFHLSS YIMNSEGDEP
     SSKRRKHQGT IQRHWEYICN HNKENTKILG DENVDPICED SENKFEFSVM SYNILSQDLL
     EDNSHLYKHC RRPVLHWSFR FPNILKEIKH FDADVLCLQE VQEDHYGTEI RPSLESLGYH
     CEYKMRTGRK PDGCAICFKH SKFSLLSVNP VEFYRRDVPL LDRDNVGLVL LLQPKIPSAT
     SPAICVANTH LLYNPRRGDI KLTQLAMLLA EISSVAHQKD GRFCPIVMCG DFNSVPGSPL
     YSFIKEGKLN YEGLAIGKVS GQEQSSRGQR ILSIPIWPPN LGISQNCVYE VQQVPKVEKP
     DGDLTQPELD KTEVLVTAEK LSSNLQHHFS LSSVYSHYLP DTGIPEVTTC HSRSAVTVDY
     IFYSAEKEGV AEQPGAEVAL VGGLKLLARL SLLTEQDLWT VNGLPNENNS SDHLPLLAKF
     RLEL