ID   ANGR_VIBAN              Reviewed;        1048 AA.
AC   P0DJH0; P19828;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2012, sequence version 1.
DT   03-AUG-2022, entry version 31.
DE   RecName: Full=Anguibactin system regulator;
GN   Name=angR;
OS   Vibrio anguillarum (Listonella anguillarum).
OG   Plasmid pJHC1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=55601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=531A;
RX   PubMed=8335354; DOI=10.1128/iai.61.8.3228-3233.1993;
RA   Tolmasky M.E., Actis L.A., Crosa J.H.;
RT   "A single amino acid change in AngR, a protein encoded by pJM1-like
RT   virulence plasmids, results in hyperproduction of anguibactin.";
RL   Infect. Immun. 61:3228-3233(1993).
CC   -!- FUNCTION: Bifunctional protein that plays an essential role in
CC       virulence. Plays a role in both the production of the siderophore
CC       anguibactin and the regulation of iron transport genes (By similarity).
CC       {ECO:0000250}.
CC   -!- PATHWAY: Siderophore biosynthesis; anguibactin biosynthesis.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Lacks the conserved Ser at position 1000 required for covalent
CC       attachment of 4-phosphopantetheine. {ECO:0000305}.
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DR   EMBL; Z12000; CAA78044.1; -; Genomic_DNA.
DR   PIR; JQ0416; YGVCAR.
DR   RefSeq; WP_020977922.1; NZ_VSLF01000048.1.
DR   AlphaFoldDB; P0DJH0; -.
DR   SMR; P0DJH0; -.
DR   STRING; 55601.VANGNB10_67p038; -.
DR   OrthoDB; 572620at2; -.
DR   UniPathway; UPA00016; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   Gene3D; 1.10.1200.10; -; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.30.559.10; -; 1.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   Pfam; PF00668; Condensation; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   TIGRFAMs; TIGR01733; AA-adenyl-dom; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Ion transport; Iron; Iron transport; Ligase;
KW   Plasmid; Transcription; Transcription regulation; Transport.
FT   CHAIN           1..1048
FT                   /note="Anguibactin system regulator"
FT                   /id="PRO_0000193064"
FT   DOMAIN          965..1039
FT                   /note="Carrier"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
SQ   SEQUENCE   1048 AA;  118398 MW;  494C2B600A5C6EC7 CRC64;
     MNQNEHPFAF PETKLPLTSN QNWQLSTQRQ RTEKKSITNF TYQEFDYENI SRDTLERCLT
     TIIKHHPIFG AKLSDDFYLH FPSKTHIETF AVNDLSNALK QDIDKQLADT RSAVTKSRSQ
     AIISIMFSIL PKNIIRLHVR FNSVVVDNPS VTLFFEQLTQ LLSGSPLSFL NQEQTISAYN
     HKVNNELLSV DLESARWNEY ILTLPSSANL PTICEPEKLD ETDITRRCIT LSQRKWQQLV
     TVSKKHNVTP EITLASIFST VLSLWGNQKY LMMRFDITKI NDYTGIIGQF TEPLLVGMSG
     FEQSFLSLVK NNQKKFEEAY HYDVKVPVFQ CVNKLSNISD SHRYPANITF SSELLNTNHS
     KKAVWGCRQS ANTWLSLHAV IEQEQLVLQW DSQDAIFPKD MIKDMLHSYT DLLDLLSQKD
     VNWAQPLPTL LPKHQESIRN KINQQGDLEL TKELLHQRFF KNVESTPNAL AIIHGQESLD
     YITLASYAKS CAGALTEAGV KSGDRVAVTM NKGIGQIVAV LGILYAGAIY VPVSLDQPQE
     RRESIYQGAG INVILINESD SKNSPSNDLF FFLDWQTAIK SEPMRSPQDV APSQPAYIIY
     TSGSTGTPKG VVISHQGALN TCIAINRRYQ IGKNDRVLAL SALHFDLSVY DIFGLLSAGG
     TIVLVSELER RDPIAWCQAI EEHNVTMWNS VPALFDMLLT YATCFNSIAP SKLRLTMLSG
     DWIGLDLPQR YRNYRVDGQF IAMGGATEAS IWSNVFDVEK VPMEWRSIPY GYPLPRQQYR
     VVDDLGRDCP DWVAGELWIG GDGIALGYFD DELKTQAQFL HIDGHAWYRT GDMGCYWPDG
     TLEFLGRRDK QVKVGGYRIE LGEIEVALNN IPGVQRAVAI AVGNKDKTLA AFIVMDSEQA
     PIVTAPLDAE EVQLLLNKQL PNYMVPKRII FLETFPLTAN GKVDHKALTR MTNREKKTSQ
     SINKPIITAS EDRVAKIWND VLGPTELYKS SDFFLSGGDA YNAIEVVKRC HKAGYLIKLS
     MLYRYSTIEA FAIIMDRCRL APQEEAEL